3618-40-4

Basic information

• Product Name: 2-Methyleneoctanoic acid methyl ester
• Synonyms: 2-Methyleneoctanoic acid methyl ester
• CAS NO: 3618-40-4
• Molecular Formula: C₁₀H₁₈O₂
• Molecular Weight: 170.25
• Mol File: 3618-40-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Methyleneoctanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyleneoctanoic acid methyl ester(3618-40-4)
• EPA Substance Registry System: 2-Methyleneoctanoic acid methyl ester(3618-40-4)

Safety Data

• Hazardous Substances Data: 3618-40-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 629-05-0 n-octyne 
• 201230-82-2 carbon monoxide 
• 124-38-9 carbon dioxide 
• 74-88-4 methyl iodide 

Relevant articles and documents

Novel multi-dentate phosphines for Pd-catalyzed alkoxycarbonylation of alkynes promoted by H2O additive

A series of novel multi (bi-/tri-/tetra-)-dentate phosphines with good robustness against water and oxygen were synthesized and fully characterized. It was found that the developed ionic tri-dentate phosphine (L2′) enabled Pd-catalyzed alkoxycarbonylation of alkynes most efficiently while H2O was used as an additive instead of acid. As for L2′, its unique steric configuration with two types of potential P-P chelation modes (P?P distance of 4.31 ? and 4.36 ? respectively) to Pd-centre rendered the corresponding Pd-catalyst high activity and good stability for alkoxycarbonylation of alkynes. The in situ FT-IR analysis also verified that the formation and stability of Pd–H active species were greatly facilitated with the presence of L2′ as well as H2O additive. In addition, as an ionic phosphine, L2′ based PdCl2(MeCN)2 system immobilized in RTIL of [Bmim]NTf2 could be recycled for 7 runs without obvious activity loss or metal leaching.

From Stoichiometry to Catalysis: Electroreductive Coupling of Alkynes and Carbon Dioxide with Nickel-Bipyridine Complexes. Magnesium Ions as the Key for Catalysis

The incorporation of carbon dioxide into nonactivated alkynes catalyzed by electrogenerated nickel-bipyridine complexes affords α,β-unsaturated acids in moderate to good yields.The electrocarboxylation reaction was undertaken on a preparative scale in the presence of a sacrificial magnesium anode: the formation of acids from alkynes is stoichiometric with respect to the nickel complex if performed in a two-compartment cell but can be made catalytic in a single-compartment cell.An intermediate nickelacycle was isolated from the reaction with 4-octyne.The cleavage ofthis metallacycle by magnesium ions is the key step to explain catalysis.