36194-82-8 Usage
Description
5-BROMO-2-HYDROXY-3-METHYLBENZENECARBOXYLIC ACID is a chemical compound with the molecular formula C8H7BrO3, belonging to the benzoic acid derivatives. It features a bromine atom, a hydroxyl group, and a methyl group, which contribute to its unique chemical properties and potential applications in various fields.
Uses
Used in Organic Synthesis:
5-BROMO-2-HYDROXY-3-METHYLBENZENECARBOXYLIC ACID is used as a starting material in organic synthesis for the production of other chemicals and pharmaceuticals. Its unique structure allows for versatile chemical reactions and modifications, making it a valuable component in the synthesis of various compounds.
Used in Pharmaceutical Research:
In Pharmaceutical Research, 5-BROMO-2-HYDROXY-3-METHYLBENZENECARBOXYLIC ACID is used as a precursor for the development of new drugs. Its structural similarities with certain nonsteroidal anti-inflammatory drugs (NSAIDs) suggest potential applications in the creation of anti-inflammatory and analgesic medications.
Used in Anti-inflammatory and Analgesic Drug Development:
5-BROMO-2-HYDROXY-3-METHYLBENZENECARBOXYLIC ACID is used as a key component in the development of anti-inflammatory and analgesic drugs. Its chemical structure allows for the design of new medications that may offer improved efficacy, reduced side effects, or novel mechanisms of action compared to existing treatments.
Used in Antioxidant Research:
5-BROMO-2-HYDROXY-3-METHYLBENZENECARBOXYLIC ACID is studied for its potential antioxidant properties, which could be harnessed in the development of new antioxidants for various applications, including pharmaceuticals, cosmetics, and food preservation.
Used in Antimicrobial Research:
In Antimicrobial Research, 5-BROMO-2-HYDROXY-3-METHYLBENZENECARBOXYLIC ACID is investigated for its potential antimicrobial properties. If proven effective, it could be incorporated into the development of new antimicrobial agents to combat drug-resistant bacteria and other pathogens.
Used in Research and Development Applications:
5-BROMO-2-HYDROXY-3-METHYLBENZENECARBOXYLIC ACID is utilized in various research and development applications across different industries. Its unique chemical properties and potential applications make it a valuable compound for further exploration and innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 36194-82-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,1,9 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 36194-82:
(7*3)+(6*6)+(5*1)+(4*9)+(3*4)+(2*8)+(1*2)=128
128 % 10 = 8
So 36194-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BrO3/c1-4-2-5(9)3-6(7(4)10)8(11)12/h2-3,10H,1H3,(H,11,12)
36194-82-8Relevant articles and documents
Live-Cell Protein Modification by Boronate-Assisted Hydroxamic Acid Catalysis
Adamson, Christopher,Kajino, Hidetoshi,Kanai, Motomu,Kawashima, Shigehiro A.,Yamatsugu, Kenzo
supporting information, p. 14976 - 14980 (2021/09/29)
Selective methods for introducing protein post-translational modifications (PTMs) within living cells have proven valuable for interrogating their biological function. In contrast to enzymatic methods, abiotic catalysis should offer access to diverse and new-to-nature PTMs. Herein, we report the boronate-assisted hydroxamic acid (BAHA) catalyst system, which comprises a protein ligand, a hydroxamic acid Lewis base, and a diol moiety. In concert with a boronic acid-bearing acyl donor, our catalyst leverages a local molarity effect to promote acyl transfer to a target lysine residue. Our catalyst system employs micromolar reagent concentrations and affords minimal off-target protein reactivity. Critically, BAHA is resistant to glutathione, a metabolite which has hampered many efforts toward abiotic chemistry within living cells. To showcase this methodology, we installed a variety of acyl groups inE. colidihydrofolate reductase expressed within human cells. Our results further establish the well-known boronic acid-diol complexation as abona fidebio-orthogonal reaction with applications in chemical biology and in-cell catalysis.
NK-1 AND SEROTONIN TRANSPORTER INHIBITORS
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Page/Page column 88, (2010/11/28)
The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both.
