362-47-0

Basic information

• Product Name: Methanone, (5-fluoro-2-hydroxyphenyl)phenyl-
• CAS NO: 362-47-0
• Molecular Formula: C13H9FO2
• Molecular Weight: 216.212
• Mol File: 362-47-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Methanone, (5-fluoro-2-hydroxyphenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (5-fluoro-2-hydroxyphenyl)phenyl-(362-47-0)
• EPA Substance Registry System: Methanone, (5-fluoro-2-hydroxyphenyl)phenyl-(362-47-0)

Safety Data

• Hazardous Substances Data: 362-47-0(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 371-41-5 4-Fluorophenol 
• 611-71-2 MANDELIC ACID 
• 591-50-4 iodobenzene 
• 347-54-6 5-fluoro-2-hydroxybenzaldehyde 
• 65-85-0 benzoic acid 
• 1765-93-1 4-fluoroboronic acid 
• 880473-80-3 2-(4-fluorophenoxy)isoindoline-1,3-dione 
• 1443440-59-2 (4-fluoro-N-phenoxy)acetamide 
• 501-65-5 diphenyl acetylene 
• 1173294-78-4 2-(4-fluorophenoxy)pyridine 
• 100-51-6 benzyl alcohol 
• 1173294-86-4 (5-fluoro-2-(pyridin-2-yloxy)phenyl)(phenyl)methanone 
• 98-80-6 phenylboronic acid 

Downstream Products

• 62665-86-5 C₂₄H₃₀FNO₃ 
• 67059-95-4 α-phenyl-α-methyl-(5-fluoro-2-hydroxy)-phenyl-methanol 
• 62666-35-7 N-(4-Fluoro-benzyl)-4-{[1-(5-fluoro-2-hydroxy-phenyl)-1-phenyl-meth-(E)-ylidene]-amino}-butyramide 
• 62666-25-5 N-Benzyl-4-{[1-(5-fluoro-2-hydroxy-phenyl)-1-phenyl-meth-(E)-ylidene]-amino}-butyramide 
• 62666-21-1 N-Cyclohexyl-4-{[1-(5-fluoro-2-hydroxy-phenyl)-1-phenyl-meth-(E)-ylidene]-amino}-butyramide 
• 62666-24-4 4-{[1-(5-Fluoro-2-hydroxy-phenyl)-1-phenyl-meth-(E)-ylidene]-amino}-N-phenyl-butyramide 
• 62666-23-3 N-Cyclopentyl-4-{[1-(5-fluoro-2-hydroxy-phenyl)-1-phenyl-meth-(E)-ylidene]-amino}-butyramide 
• 62666-22-2 N-Cyclopropyl-4-{[1-(5-fluoro-2-hydroxy-phenyl)-1-phenyl-meth-(E)-ylidene]-amino}-butyramide 
• 62666-28-8 C₂₅H₃₃FN₂O₂ 
• 62666-29-9 C₂₁H₂₃FN₂O₂ 
• 62666-30-2 C₂₀H₂₃FN₂O₂ 
• 62666-27-7 C₁₉H₂₁FN₂O₂ 
• 62666-26-6 C₁₈H₁₉FN₂O₂ 
• 62666-09-5 C₁₇H₁₇FN₂O₂ 

Relevant articles and documents

Water-Tolerant ortho-Acylation of Phenols

A metal-free, water-tolerant, and one-pot process for ortho-acylation of phenols promoted by the iodine source/hydrogen peroxide system has been developed. This transformation undergoes ether formation, iodocyclization, C-C bond cleavage, and oxidative hydrolysis in a one-step manner, which is supported by control experiments.

Nickel-Catalyzed Decarbonyloxidation of 3-Aryl Benzofuran-2(3H)-ones to 2-Hydroxybenzophenones

We have developed a protocol to facilitate the nickel-catalyzed decarbonyloxidation of 3-aryl benzofuran-2(3H)-ones to 2-hydroxybenzophenones under mild conditions, which is an efficient approach for the decarbonyloxidation of lactones in organic synthesis. A diverse range of substrates can undergo C(O)-O/C(O)-C bond cleavage to generate the target products in good yields. These 2-hydroxybenzophenones can be converted into a variety of compounds via reactions such as esterification, cyclization, and reduction.

Efficient microwave-assisted direct C-benzoylation of phenols and naphthols with benzoic acid catalyzed by bismuth triflate under solvent-free or ionic liquid conditions

An efficient and simple route for the synthesis of ortho-hydroxyaryl ketones has been developed. The microwave-assisted direct C-benzoylation of phenols and naphthols in the presence of metal triflates afforded the corresponding ortho-hydroxyaryl ketones in moderate to excellent yields. Bismuth triflate showed the best catalytic performance compared to other metal triflates. The protocol has advantages including short reaction times, high chemoselectivity towards C-acylation, and simple work-up. Additionally, bismuth triflate can be easily recovered and reused several times without significant loss of catalytic performance.