364046-18-4Relevant articles and documents
Imino-C-nucleoside Synthesis: Heteroaryl Lithium Carbanion Additions to A Carbohydrate Cyclic Imine and Nitrone
Evans, Gary B.,Furneaux, Richard H.,Hausler, Herwig,Larsen, Janus S.,Tyler, Peter C.
, p. 2217 - 2220 (2004)
Promotion by Lewis acid of the addition of some aryllithiums to a carbohydrate-based imine, which has allowed a more facile synthesis of some imino-C-nucleoside analogues, is described. Use of the corresponding nitrone does not assist in some cases, but l
COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE
-
, (2013/11/05)
Provided are compounds of Formula (I) as described herein. Compounds of Formula (I) are useful in methods of inhibiting viral RNA polymerase activity and viral replication. Also provided are pharmaceutical compositions comprising compounds of Formula (I), as well as methods of treating viral infections using compounds of Formula (I).
Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins
Evans,Furneaux,Hutchison,Kezar,Morris, Jr.,Schramm,Tyler
, p. 5723 - 5730 (2007/10/03)
Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.