36440-59-2

Upstream product

• 7397-06-0 4-t-butyl-o-xylene 
• 5779-93-1 2,3-dimethylbenzaldehyde 
• 292638-85-8 acrylic acid methyl ester 
• 1490-25-1 succinic acid monomethylester chloride 
• 86306-28-7 methyl β-(2,3-dimethyl-5-t-butylbenzoyl)propanoate 
• 576-23-8 2,3-dimethylbromobenzene 

Downstream Products

• 34995-04-5 β-(2,3-Dimethylbenzoyl)propionsaeure 
• 13621-31-3 methyl γ-(2,3-dimethylphenyl)butanoate 
• 86322-98-7 2-methyl-5-(2,3-dimethylphenyl)pentan-2-ol 
• 641-91-8 1,2,5-trimethylnaphthalene 
• 13621-30-2 4-(2,3-dimethylphenyl)butanoic acid 
• 32281-65-5 5,6-dimethyl-1,2,3,4-tetrahydronaphthalen-1-one 

Relevant academic research and scientific papers

Enantioselective total synthesis and biological evaluation of (-)-solanacol

An enantioselective synthesis of the phenyl ring-containing strioglactone, (-)-solanocol, is described. Application of a Dynamic Kinetic Resolution (DKR) in the stereo-defining step enabled a step-economical synthesis to be achieved, and allowed access to natural and non-natural enantiomers with equal facility. Results of seed germination assays and Differential Scanning Fluorimetry (DSF) measurements with the known strigolactone receptor protein, Decreased Apical Dominance 2 (DAD2), are reported.

Synthesis of 1,1,5,6-Tetramethyltetralin, a Nonsesquiterpenic Constituent of Isocoma wrightii

The synthesis of 1,1,5,6-tetramethyltetralin (1) has been achieved starting from 4-t-butyl-o-xylene (3) via the keto ester (6).De-t-butylation of 6 to 8, followed by Clemmensen reduction, Grignard reaction and cyclodehydration gives 1.