3649-86-3

Upstream product

• 106-95-6 allyl bromide 
• 917-54-4 methyllithium 
• 4680-20-0 2-(5,5,6-trimethylbicyclo[2.2.1]hept-exo-2-yl)phenol 
• 3292-04-4 2-exo-6-exo-5,5,6-trimethylbicyclo<2.2.1>heptan-2-ol 
• 105-36-2 ethyl bromoacetate 
• 53803-33-1 6-Oxocamphene 

Downstream Products

• 120676-74-6 2,2-di(2-cyclohexyl-2-propylperoxy)-5,5,6-trimethylbicyclo<2.2.1>heptane 
• 3732-31-8 1,1'-Biadamantane 
• 123299-34-3 endo-3-butyl-1,7,7-trimethylbicyclo<2.2.1>hept-exo-2-ylbenzamide 
• 123299-36-5 endo-6-butyl-1,7,7-trimethylbicyclo<2.2.1>hept-exo-2-ylbenzamide 
• 15373-31-6 α-campholenonitrile 

Relevant academic research and scientific papers

5,5,6-Trimethylbicyclo[2.2.1]heptan-2-one in the synthesis of carbocyclic analogs of prostaglandin endoperoxides

1,3-Dipolar cycloaddition of nitrile oxides to 5,5,6-trimethyl-exo-2-ethynylbicyclo[2.2.1]heptanendo-2-ol yields the corresponding 2-(isoxazol-5-yl) derivatives. Opening of the isoxazole ring in the latter gives rise to prostanoid precursors with partiall

REACTION OF 3-BROMOISOCAMPHANONE WITH METHYLLITHIUM

The reaction of 3-bromoisocamphanone with methyllithium gives a multicomponent mixture of alicyclic alcohols and ketones, and the proportion of the individual components depends on the ratio of the reagents and on the order of addition.One of the main reaction products endo-2-hydroxy-2,3,5,5,6-pentamethylbicycloheptane reacts with acetonitrile under the conditions of the Ritter reaction without rearrangement of the hydrocarbon skeleton and forms exo-2-acetylamino-2,3,5,5,6-pentamethylbicycloheptane.