365441-25-4

Upstream product

• 67-56-1 methanol 
• 91510-69-9 (1R,2S,3R,4R,5R)-2,3-Bis-benzyloxy-4-methyl-6,8-dioxa-bicyclo[3.2.1]octane 
• 65190-43-4 4-O-benzyl-2-methyl-1,6-anhydro-β-D-glucopyranose 
• 100-39-0 benzyl bromide 

Downstream Products

• 365441-21-0 (2R,3R,4R,5S,6R)-4,5-Bis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-tetrahydro-pyran-2-carbaldehyde 
• 365441-09-4 (2R,3R,4R,5S,6R)-4,5-Bis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-tetrahydro-pyran-2-carboxylic acid methoxy-methyl-amide 
• 627537-41-1 (1R,4S,5R,6R)-1-((2R,3R,4R,5S,6R)-4,5-Bis-benzyloxy-6-hydroxymethyl-3-methyl-tetrahydro-pyran-2-yl)-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-10-trityloxy-decane-1,4-diol 
• 365441-29-8 2,2-dimethyl-propionic acid 3,4-bis-benzyloxy-6-{1-(tert-butyl-dimethyl-silanyloxy)-2-[2-(tert-butyl-dimethyl-silanyloxy)-8-hydroxy-4-(4-methoxy-benzyloxy)-3-methyl-octyl]-allyl}-5-methyl-tetrahydro-pyran-2-ylmethyl ester 
• 627537-33-1 2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-1,4-dihydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-10-trityloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester 
• 365441-18-5 (4S,5S,6R)-1-[(2R,3R,4R,5S,6R)-4,5-Bis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-tetrahydro-pyran-2-yl]-4-(tert-butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-10-trityloxy-decan-1-one 
• 365441-19-6 (1R,4S,5S,6R)-1-[(2R,3R,4R,5S,6R)-4,5-Bis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-tetrahydro-pyran-2-yl]-4-(tert-butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-10-trityloxy-decan-1-ol 
• 365441-30-1 2,2-dimethyl-propionic acid 3,4-bis-benzyloxy-6-{1-(tert-butyl-dimethyl-silanyloxy)-2-[2-(tert-butyl-dimethyl-silanyloxy)-8-(tert-butyl-diphenyl-silanyloxy)-4-(4-methoxy-benzyloxy)-3-methyl-octyl]-allyl}-5-methyl-tetrahydro-pyran-2-ylmethyl ester 
• 365441-22-1 2,2-dimethyl-propionic acid 3,4-bis-benzyloxy-6-{1-(tert-butyl-dimethyl-silanyloxy)-2-[2-(tert-butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-3-methyl-8-trityloxy-octyl]-allyl}-5-methyl-tetrahydro-pyran-2-ylmethyl ester 
• 365441-13-0 (2R,3R,4R,5S,6R)-4,5-Bis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-tetrahydro-pyran-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthetic studies on altohyrtins (spongistatins): Synthesis of the C29-C44 (EF) portion

The C29-C44 portion of altohyrtins (spongistatins) has been prepared from 1,5-pentanediol and D-glucose in a stereoselective manner. The convergent synthesis relied on a coupling reaction of the C29-C37 vinyl bromide and the C38-C44 Weinreb amide, diaster