366-49-4

Basic information

• Product Name: 2-Acetamido-4-fluorotoluene
• Synonyms: 2-Acetamido-4-fluorotoluene;N-(5-fluoro-2-methylphenyl)acetamide;N-Acetyl 5-fluoro-2-methylaniline;Acetamide, N-(5-fluoro-2-methylphenyl)-
• CAS NO: 366-49-4
• Molecular Formula: C₉H₁₀FNO
• Molecular Weight: 167.182
• Mol File: 366-49-4.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 281.2°C at 760 mmHg
• Flash Point: 123.9°C
• Appearance: /
• Density: 1.169g/cm³
• Vapor Pressure: 0.00361mmHg at 25°C
• Refractive Index: 1.546
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-Acetamido-4-fluorotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Acetamido-4-fluorotoluene(366-49-4)
• EPA Substance Registry System: 2-Acetamido-4-fluorotoluene(366-49-4)

Safety Data

• Hazardous Substances Data: 366-49-4(Hazardous Substances Data)

Usage

General Description

2-Acetamido-4-fluorotoluene, also known as N-(4-fluorophenyl)acetamide, is a chemical compound with the molecular formula C9H10NO. It is a substituted aniline derivative with a fluorine atom and an acetamido group attached to a toluene ring. 2-Acetamido-4-fluorotoluene is used in the synthesis of various pharmaceuticals, agrochemicals, and organic compounds. It has also been studied for its potential applications in the development of new drugs and as a building block for organic synthesis. 2-Acetamido-4-fluorotoluene is considered to be a hazardous chemical and should be handled and stored with proper safety precautions.

InChI:InChI=1/C9H10FNO/c1-6-3-4-8(10)5-9(6)11-7(2)12/h3-5H,1-2H3,(H,11,12)

Upstream product

• 367-29-3 3-fluoro-6-methylaniline 
• 75-36-5 acetyl chloride 
• 351-28-0 N-(3-fluorophenyl)acetamide 
• 112359-25-8 5-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate 
• 446-10-6 2-nitro-4-fluorotoluene 
• 108-24-7 acetic anhydride 

Downstream Products

• 394-27-4 2-acetamido-4-fluorobenzoic acid 
• 446-32-2 4-fluoroanthranilic acid 
• 633327-49-8 N-(5-fluoro-2-methyl-4-nitrophenyl)acetamide 
• 633335-80-5 N-(4-bromo-5-fluoro-2-methylphenyl)acetamide 
• 30170-08-2 2-acetamido-4-fluoro-5-sulphamyltoluene 
• 633335-81-6 1-(5-bromo-6-fluoro-1H-indazol-1-yl)ethan-1-one 
• 105391-70-6 5-bromo-6-fluoro-1H-indazole 
• 1126425-15-7 6-fluoro-1H-indazole-5-carbaldehyde 
• 633327-50-1 5-fluoro-2-methyl-4-nitrophenylamine 
• 633327-51-2 5-nitro-6-fluoro-1H-indazole 

Relevant articles and documents

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3-(1H-PYRROLO[2,3-B]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF

Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF

Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.