367526-62-3Relevant academic research and scientific papers
Novel short-step synthesis of functionalized γ-phenyl-β- hydroxybutenoates and their cyclization to 4-hydroxycoumarins via the N-hydroxybenzotriazole methodology
Athanasellis, Giorgos,Melagraki, Georgia,Chatzidakis, Haralambos,Afantitis, Antreas,Detsi, Anastasia,Igglessi-Markopoulou, Olga,Markopoulos, John
, p. 1775 - 1782 (2007/10/03)
A novel method for the synthesis of functionalized 3-substituted 4-hydroxycoumarins is reported. C-Acylation compounds were derived from the reaction of the N-hydroxybenzotriazole ester of the functionalized acetyl salicylic acids and a variety of active methylene compounds and cyclized to the title compounds. The synthesis is simple and the compounds are produced in yields varying from 39 to 80%. The structure of the newly prepared C-acylation compounds was thoroughly studied through NMR spectroscopy for the first time in the literature.
A highly practical route to 2-methylchromones from 2-acetoxybenzoic acids
Jung,Min,Park
, p. 1837 - 1845 (2007/10/03)
2-Methylchromones were accessed via a keto ester condensation on 2-acetoxybenzoyl chloride, followed by cyclization and decarboxylation. No column chromatography was required in the process.
