36771-65-0Relevant academic research and scientific papers
GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE
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, (2021/01/22)
Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.
GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE
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Paragraph 001936; 001937; 001939; 002122; 002123; 002124, (2019/07/17)
Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.
Iron-catalysed cross-coupling of halohydrins with aryl aluminium reagents: A protecting-group-free strategy attaining remarkable rate enhancement and diastereoinduction
Kawamura, Shintaro,Kawabata, Tatsuya,Ishizuka, Kentaro,Nakamura, Masaharu
supporting information; experimental part, p. 9376 - 9378 (2012/09/22)
Non-protected halohydrins are cross-coupled with aryl aluminium reagents to produce aryl alkanols in the presence of the iron-bisphosphine catalysts. Remarkable reaction rate enhancement and diastereoinduction are realized by the in situ generated aluminium alkoxides, offering a new method for the reactivity and selectivity control of the iron-catalysed cross-coupling reaction.
LIQUID-CRYSTALLINE COMPOUNDS OF THE ALICYCLIC SERIES III. SYNTHESIS AND ISOMORPHISM OF ETHERS AND ESTERS CONTAINING THE PHENYLCYCLOHEXANE FRAGMENT
Karamysheva, L. A.,Torgova, S. I.,Agafonova, I. F.,Geivandov, R. Kh.,Bykova, V. V.,Burylin, P. A.
, p. 736 - 741 (2007/10/02)
A series of ethers and esters exhibiting mesomorphous characteristics were obtained from para-X-substituted trans-4-phenylcyclohexanols, trans-4-phenylcyclohexanecarboxylic acids (X = H, F, I, NO2, NH2, CN) and trans-1-hydroxymethyl-4-(p-cyanophenyl)cyclohexane.
