367944-77-2

Upstream product

• 544-92-3 copper(I) cyanide 
• 144896-92-4 (5S)-5-phenylmorpholin-2-one 
• 78-84-2 isobutyraldehyde 

Downstream Products

• 367944-95-4 (R)-2-((S)-2-Hydroxy-5-phenyl-morpholin-4-yl)-3-methyl-butyronitrile 
• 640-68-6 D-Val-OH 
• 367944-96-5 (R)-3-Methyl-2-((S)-3-phenyl-2,3-dihydro-[1,4]oxazin-4-yl)-butyronitrile 
• 367944-98-7 Formic acid (S)-2-[((R)-1-cyano-2-methyl-propyl)-formyl-amino]-2-phenyl-ethyl ester 

Relevant academic research and scientific papers

Diastereocontrolled strecker reaction using (S)-5-phenylmorpholin-2-one

Iminium ions derived from (S)-5-phenylmorpholin-2-one 1 undergo diastereoselective Strecker reactions using copper(I) cyanide and anhydrous hydrochloric acid; the major adducts may be degraded to D-α-amino acids.