367952-82-7 Usage
Uses
(2R,4R)-Argatroban (A769000) intermediate.
Check Digit Verification of cas no
The CAS Registry Mumber 367952-82-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,7,9,5 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 367952-82:
(8*3)+(7*6)+(6*7)+(5*9)+(4*5)+(3*2)+(2*8)+(1*2)=197
197 % 10 = 7
So 367952-82-7 is a valid CAS Registry Number.
367952-82-7Relevant articles and documents
A short synthesis of argatroban: A potent selective thrombin inhibitor
Cossy, Janine,Belotti, Damien
, p. 1989 - 1992 (2007/10/03)
Argatroban was synthesized in seven steps from 4-methylpiperidine. The condensation of (±)-trans-benzyl 4-methylpipecolic acid ester with Nα-Boc-Nω-nitro-L-arginine led to two diastereomers that were separated. One of them is the precursor of argatroban.
