36926-81-5

Basic information

• Product Name: 2-amino-6-methoxypyridine-3,5-dicarbonitrile
• CAS NO: 36926-81-5
• Molecular Formula: C₈H₆N₄O
• Molecular Weight: 174.1594
• Mol File: 36926-81-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 383.2°C at 760 mmHg
• Flash Point: 185.6°C
• Density: 1.35g/cm³
• Vapor Pressure: 4.47E-06mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: 2-amino-6-methoxypyridine-3,5-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-6-methoxypyridine-3,5-dicarbonitrile(36926-81-5)
• EPA Substance Registry System: 2-amino-6-methoxypyridine-3,5-dicarbonitrile(36926-81-5)

Safety Data

• Hazardous Substances Data: 36926-81-5(Hazardous Substances Data)

Usage

Abbreviation

AMPC

Structure

A pyridine derivative

Functional Groups

Two amino groups
One methoxy group
Two cyano groups attached to the pyridine ring

Role in Pharmaceutical Industry

Key intermediate in the production of Tenofovir Disoproxil Fumarate (TDF), used to treat HIV and chronic hepatitis B
Used as a pharmaceutical intermediate in the synthesis of other drugs

Importance

Crucial chemical in the pharmaceutical industry
Plays a significant role in producing life-saving medications for various diseases

Upstream product

• 51768-01-5 2-amino-6-chloropyridine-3,5-dicarbonitrile 
• 124-41-4 sodium methylate 

Downstream Products

• 1243606-72-5 2-amino-6-(3-phenylpropoxy)pyridine-3,5-dicarbonitrile 
• 1263199-64-9 5-amino-7-benzyl-2-methoxy-6,7,8,9-tetrahydropyrido[2,3-b][1,6]naphthyridine-3-carbonitrile 

Relevant articles and documents

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Medicine comprising dicyanopyridine derivative

Compounds having a high conductance-type of calcium-activated K channel opening effect and a smooth muscle relaxant effect for bladder based on the K-channel opening effect, which can be used in treating pollakiuria and urinary incontinence, are provided.