3695-93-0

Basic information

• Product Name: (E)-ALPHA-(4-CHLOROPHENYL)CINNAMONITRILE
• Synonyms: Benzal-(4'-chlor-benzyl-cyanid);Benzeneacetonitrile, 4-chloro-alpha-(phenylmethylene)-;F 2389;f2389;Nsc89132;(E)-ALPHA-(4-CHLOROPHENYL)CINNAMONITRILE;A-(P-CHLOROPHENYL)CINNAMONITRILE;ALPHA-(P-CHLOROPHENYL)CINNAMOMNITRILE
• CAS NO: 3695-93-0
• Molecular Formula: C₁₅H₁₀ClN
• Molecular Weight: 239.7
• Mol File: 3695-93-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 113-117 °C(lit.)
• Boiling Point: 381.83°C (rough estimate)
• Flash Point: 150.7 °C
• Appearance: /
• Density: 1.1687 (rough estimate)
• Vapor Pressure: 1.23E-05mmHg at 25°C
• Refractive Index: 1.5868 (estimate)
• CAS DataBase Reference: (E)-ALPHA-(4-CHLOROPHENYL)CINNAMONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-ALPHA-(4-CHLOROPHENYL)CINNAMONITRILE(3695-93-0)
• EPA Substance Registry System: (E)-ALPHA-(4-CHLOROPHENYL)CINNAMONITRILE(3695-93-0)

Safety Data

• Hazard Codes: Xn
• Statements: 41-42/43
• Safety Statements: 22-26-36/37/39-45
• WGK Germany: 3
• Hazardous Substances Data: 3695-93-0(Hazardous Substances Data)

Usage

General Description

(E)-alpha-(4-chlorophenyl)cinnamonitrile is a chemical compound with the molecular formula C16H10ClN. It is also known by the trade name KFC-1, and is used in the synthesis of pharmaceuticals and other organic compounds. This chemical is a clear, colorless to slightly yellow liquid, and has a characteristic sweet, floral odor. It is primarily used in the production of perfumes and flavors, as well as in the pharmaceutical industry for drug synthesis. Additionally, (E)-alpha-(4-chlorophenyl)cinnamonitrile has potential applications in materials science and nanotechnology. It is important to handle this chemical with care, as it may cause skin and eye irritation, and can be harmful if ingested or inhaled.

InChI:InChI=1/C15H10ClN/c16-15-8-6-13(7-9-15)14(11-17)10-12-4-2-1-3-5-12/h1-10H/b14-10-

Upstream product

• 1529-41-5 3-chloro-benzeneacetonitrile 
• 100-52-7 benzaldehyde 
• 108-88-3 toluene 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 140-53-4 p-chlorobenzyl cyanide 
• 141-52-6 sodium ethanolate 

Downstream Products

• 7497-44-1 2-(4-chlorophenyl)-3-phenylsuccinonitrile 
• 1398056-84-2 3-(4-chlorophenyl)-4-phenyl-1H-pyrrole 
• 1376190-83-8 ethyl 4-(4-chlorophenyl)-3-phenyl-1H-pyrrole-2-carboxylate 
• 1376190-88-3 (S)-ethyl 4-(4-chlorophenyl)-1-[2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl]-3-phenyl-1H-pyrrole-2-carboxylate 
• 1376191-93-3 (S)-4-(4-chlorophenyl)-1-(3,4-dihydroxybutyl)-N-[3-(4-methylpiperazin-1-yl)propyl]-3-phenyl-1H-pyrrole-2-carboxamide 
• 5681-31-2 2-(4-chlorophenyl)-3-phenylpropanenitrile 
• 82234-92-2 3-cyano-3-(4-chlorophenyl)-2,4,5-triphenylpyrrolidine 

Relevant articles and documents

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The invention relates to an efficient environment-friendly catalyst, and a new method for preparing double-(hetero)aromatic-ring substituted alkene under a room-temperature condition by taking water as a reaction medium. The method comprises: taking n-propylamine supported by super-paramagnetism nanometer particles and modified by ion atmosphere as a catalyst, and under the conditions of room temperature, normal pressure and water reaction medium, performing Knoevenagel condensation reaction on an (hetero)aromatic-ring substituted active alkene substance and an aromatic aldehyde, so as to obtain a corresponding double-(hetero)aromatic-ring substituted alkene derivative. The reaction yield is not obviously reduced after the supported catalyst is repeatedly used for 8 times. The method is simple in operation, high in yield, simple in catalyst recovery, good in reusability of the catalytic reaction system and mild in reaction conditions, and has good industrialization prospect.

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