37052-98-5Relevant articles and documents
Synthesis and photophysical properties of selenopheno[2,3-b]quinoxaline and selenopheno[2,3-b]pyrazine heteroacenes
Koketsu, Mamoru,Ninomiya, Masayuki,Shimozuma, Atsushi,Sonawane, Amol D.,Udagawa, Taro
, p. 4063 - 4070 (2020/06/09)
In this paper, we report the novel synthesis of three different heterocycles, namely 2-arylselenopheno[2,3-b]quinoxaline, 3-(aryl/alkylselanyl)-2-arylselenopheno[2,3-b]quinoxaline and 6-phenyl-7-(arylselanyl)selenopheno[2,3-b]pyrazine derivatives, from th
Trifluoroacetic Acid Mediated One-Pot Synthesis of Furo-Fused Quinoxalines/Pyrazines
Mohan Saini, Kapil,Kumar, Sonu,Patel, Monika,Saunthwal, Rakesh K.,Verma, Akhilesh K.
, p. 3707 - 3715 (2017/07/22)
A trifluoroacetic acid promoted step-economical one-pot approach to the synthesis of furo-fused quinoxalines/pyrazines by the reaction of 2,3-dichloroquinoxalines/pyrazines with alkynes is described. The reaction involves a selective in-situ Sonogashira c
Transition metal free hydrolysis/cyclization strategy in a single pot: Synthesis of fused furo N-heterocycles of pharmacological interest
Nakhi, Ali,Rahman, Md. Shafiqur,Seerapu, Guru Pavan Kumar,Banote, Rakesh Kumar,Kumar, Kummari Lalith,Kulkarni, Pushkar,Haldar, Devyani,Pal, Manojit
, p. 4930 - 4934 (2013/08/23)
A transition metal free tandem two-step strategy has been developed involving hydrolysis of 2-chloro-3-alkynyl quinoxalines/pyrazines followed by in situ cyclization of the corresponding 2-hydroxy-3-alkynyl intermediates in a single pot leading to fused furo N-heterocycles as potential inhibitors of sirtuins. A representative compound showed promising pharmacological properties in vitro and in vivo.