370564-77-5Relevant academic research and scientific papers
Synthesis of a conformationally restricted dipeptide analogue and its evaluation as a β-turn mimic
De Borggraeve, Wim M.,Rombouts, Frederik J.R.,Van der Eycken, Erik V.,Toppet, Suzanne M.,Hoornaert, Georges J
, p. 5693 - 5695 (2001)
Dichloropyrazinone 3 was converted into a conformationally restricted dipeptide analogue 8 by means of a Diels-Alder strategy. The β-turn characteristics of molecule 8 were examined by molecular modeling and NMR spectroscopy.
