370580-35-1 Usage
Chemical structure
1H-Indole, 5-methoxy-2-(4-methoxybenzoyl)-1-(phenylsulfonyl)is a complex chemical compound with an indole ring and various substituted groups.
Indole ring
The compound contains an indole ring, which is a bicyclic structure consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring.
Substituents
The indole ring has a 5-methoxy group attached to it, as well as a 4-methoxybenzoyl group and a phenylsulfonyl group.
Benzoyl group
The 4-methoxybenzoyl group is a benzoyl group (a phenyl ring bonded to a carbonyl group) with a methoxy group attached to the 4-position of the phenyl ring.
Phenylsulfonyl group
The phenylsulfonyl group is a phenyl ring bonded to a sulfonyl group (a sulfur atom double-bonded to an oxygen atom), which is attached to the 1-position of the indole ring.
Potential pharmaceutical applications
Due to its structural features, 1H-Indole, 5-methoxy-2-(4-methoxybenzoyl)-1-(phenylsulfonyl)- may have potential applications in the pharmaceutical industry as it could potentially interact with biological targets.
Research interest
The unique structure of the compound may make it of interest for research in organic chemistry and medicinal chemistry.
Further study
Additional research and exploration of the properties and potential uses of 1H-Indole, 5-methoxy-2-(4-methoxybenzoyl)-1-(phenylsulfonyl)- may be warranted to better understand its applications and benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 370580-35-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,0,5,8 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 370580-35:
(8*3)+(7*7)+(6*0)+(5*5)+(4*8)+(3*0)+(2*3)+(1*5)=141
141 % 10 = 1
So 370580-35-1 is a valid CAS Registry Number.
370580-35-1Relevant academic research and scientific papers
Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase
Mahboobi, Siavosh,Teller, Steffen,Pongratz, Herwig,Hufsky, Harald,Sellmer, Andreas,Botzki, Alexander,Uecker, Andrea,Beckers, Thomas,Baasner, Silke,Sch?chtele, Christoph,überall, Florian,Kassack, Matthias U.,Dove, Stefan,B?hmer, Frank-D.
, p. 1002 - 1018 (2007/10/03)
The novel lead bis(1H-2-indolyl)methanone inhibits autophosphorylation of platelet-derived growth factor (PDGF) receptor tyrosine kinase in intact cells. Various substituents in the 5- or 6-position of one indole ring increase or preserve potency, whereas
2-acyl indole derivatives and their use as antitumor agents
-
, (2008/06/13)
The invention relates to novel indole and heteroindole derivatives of the formula I to their tautomers, their stereoisomers, their mixtures and their salts, to their preparation and to the use of indole derivatives of the formula I as antitumor agents.
Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents
Mahboobi,Pongratz,Hufsky,Hockemeyer,Frieser,Lyssenko,Paper,Bürgermeister,B?hmer,Fiebig,Burger,Baasner,Beckers
, p. 4535 - 4553 (2007/10/03)
A new class of simple synthetic antimitotic compounds based on 2-aroylindoles was discovered. (5-Methoxy-1H-2-indolyl)-phenylmethanone (1) as well as analogous 3-fluorophenyl- (36) and 3-methoxyphenyl (3) derivatives displayed high cytotoxicity of IC
