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1H-Indole, 5-methoxy-2-(2-nitrobenzoyl)-1-(phenylsulfonyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

370580-60-2

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370580-60-2 Usage

Molecular structure

The compound consists of an indole ring with a methoxy group at the 5 position, a nitrobenzoyl group at the 2 position, and a phenylsulfonyl group at the 1 position.

Usage

It is used in organic synthesis and pharmaceutical research as a building block for the synthesis of a variety of biologically active compounds.

Potential applications

1H-Indole, 5-methoxy-2-(2-nitrobenzoyl)-1-(phenylsulfonyl)may have potential applications in drug discovery and development due to its structural features and potential pharmacological properties.

Biological activities and therapeutic uses

The specific biological activities and potential therapeutic uses of 1H-Indole, 5-methoxy-2-(2-nitrobenzoyl)-1-(phenylsulfonyl)- have not been extensively studied or reported.

Check Digit Verification of cas no

The CAS Registry Mumber 370580-60-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,0,5,8 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 370580-60:
(8*3)+(7*7)+(6*0)+(5*5)+(4*8)+(3*0)+(2*6)+(1*0)=142
142 % 10 = 2
So 370580-60-2 is a valid CAS Registry Number.

370580-60-2Relevant academic research and scientific papers

Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase

Mahboobi, Siavosh,Teller, Steffen,Pongratz, Herwig,Hufsky, Harald,Sellmer, Andreas,Botzki, Alexander,Uecker, Andrea,Beckers, Thomas,Baasner, Silke,Sch?chtele, Christoph,überall, Florian,Kassack, Matthias U.,Dove, Stefan,B?hmer, Frank-D.

, p. 1002 - 1018 (2007/10/03)

The novel lead bis(1H-2-indolyl)methanone inhibits autophosphorylation of platelet-derived growth factor (PDGF) receptor tyrosine kinase in intact cells. Various substituents in the 5- or 6-position of one indole ring increase or preserve potency, whereas

2-acyl indole derivatives and their use as antitumor agents

-

, (2008/06/13)

The invention relates to novel indole and heteroindole derivatives of the formula I to their tautomers, their stereoisomers, their mixtures and their salts, to their preparation and to the use of indole derivatives of the formula I as antitumor agents.

Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents

Mahboobi,Pongratz,Hufsky,Hockemeyer,Frieser,Lyssenko,Paper,Bürgermeister,B?hmer,Fiebig,Burger,Baasner,Beckers

, p. 4535 - 4553 (2007/10/03)

A new class of simple synthetic antimitotic compounds based on 2-aroylindoles was discovered. (5-Methoxy-1H-2-indolyl)-phenylmethanone (1) as well as analogous 3-fluorophenyl- (36) and 3-methoxyphenyl (3) derivatives displayed high cytotoxicity of IC

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