3717-23-5

Usage

Uses

Used in Pharmaceutical Industry:
(Z)-4-Chlorobenzaldehyde oxime is used as a chemical intermediate for the synthesis of various organic compounds, particularly in the pharmaceutical industry. It plays a crucial role in the development of new drugs and medicines due to its unique chemical properties.
Used in Agrochemical Industry:
In the agrochemical industry, (Z)-4-Chlorobenzaldehyde oxime is also utilized as a chemical intermediate. It contributes to the production of various agrochemicals, such as pesticides and fertilizers, which are essential for agricultural productivity and crop protection.
Used in Organic Chemistry:
(Z)-4-Chlorobenzaldehyde oxime serves as a reagent in certain chemical reactions within the field of organic chemistry. Its unique structure allows it to participate in specific reactions, facilitating the synthesis of complex organic molecules.
Used in Research and Development:
(Z)-4-Chlorobenzaldehyde oxime is also subject to research for its potential biological activities and pharmacological properties. Scientists are exploring its possible applications in the development of new therapeutic agents and understanding its interactions with biological systems.

InChI:InChI=1/C7H6ClNO/c8-7-3-1-6(2-4-7)5-9-10/h1-5,10H/b9-5-

Upstream product

• 3717-24-6 4-chlorobenzaldehyde oxime 
• 80055-48-7 4-chloro-benzaldehyde-(O-acetyl-seqcis-oxime ) 
• 104-88-1 4-chlorobenzaldehyde 
• 71-43-2 benzene 

Downstream Products

• 3717-24-6 4-chlorobenzaldehyde oxime 
• 623-03-0 4-Cyanochlorobenzene 
• 80055-48-7 4-chloro-benzaldehyde-(O-acetyl-seqcis-oxime ) 
• 24515-81-9 3-(4-chloro-phenyl)-5-(2,2,2-trifluoro-1-trifluoromethyl-ethylidene)-[1,4,2]oxathiazolidine 
• 7050-86-4 4-chloro-benzaldehyde-(O-carbamoyl oxime ) 
• 104-88-1 4-chlorobenzaldehyde 
• 104-86-9 4-chlorobenzylamine 
• 619-56-7 4-chlorobenzamide 
• 130966-62-0 3-(4-chlorophenyl)-4-phenylisoxazole 
• 125674-27-3 Diethyl 3-(4-chlorophenyl)-2-isoxazolin-5-ylmethylphosphonate 
• 5300-92-5 5-(bromomethyl)-3-(4-chlorophenyl)-isoxazole 
• 1140531-55-0 (E)-4-chlorobenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime 
• 1140531-54-9 (E)-4-chlorobenzaldehyde O-1-(2-oxopyrrolidin-1-yl)ethyloxime 
• 105755-37-1 4-chlorobenzohydroximoyl chloride 

Relevant academic research and scientific papers

Visible-light mediated stereospecific C(sp2)-H difluoroalkylation of (Z)-aldoximes

A visible light mediated stereospecific C(sp2)-H difluoroalkylation of (Z)-aldoximes to (E)-difluoroalkylated ketoximes has been described. In this reaction, (hetero)-aromatic and aliphatic difluoroalkylated ketoximes could be obtained with the retention of the configuration of the starting aldoximes. A preliminary mechanism study showed that a difluoromethyl radicalviaan SET pathway was involved.

Host (dealuminated Y zeolite)–guest (zirconium tetraphenylporphyrin) nanocomposite materials. An efficient catalyst in the oximation of aldehydes

In this research, zirconium tetraphenylporphyrin encapsulated into dealuminated Y zeolite (ZrTPP–DAZY) was prepared through a template synthesis method. This heterogeneous catalyst was characterized by XRD, FT-IR, DRS, UV–Vis, EDX and FESEM techniques. The amount of ZrTPP in the nanocage of dealuminated Y zeolite was estimated to be 0.0156?g/g of support. This catalytic system was employed for an efficient oximation of aldehydes under magnetic stirring conditions at room temperature and the corresponding products were obtained in 50–90% yields. This catalytic system also indicated good shape selectivity towards linear aldehydes. ZrTPP–DAZY was reused several times without any significant loss in catalytic activity.

A facile steroselective synthesis of Z-aldoximes from benzaldehyde and hydroxlaminehydrochloride in dry media

The synthesis of Z-arylaldoximes has been carried out under microwave conditions using CdSO4 as catalyst. The yields obtained were in the range 84-88%.

Catalytic performance of preyssler anion in selective oximation of aromatic aldehydes

Preyssler catalyst, H14[NaP5W30O110], catalyzes the aldoximation of aromatic aldehydes for the synthesis of Z-isomers in conventional manner and under microwave irradiation. Both pure acid and silica-supported catalysts were used and their activities compared with common catalysts such as K2CO3 and CuSO4. The Preyssler is the catalyst for this reaction.

AlPW12O40 and AlPMo12O40 as highly effective and eco-friendly catalysts for aldoximation of aldehydes under solvent-free conditions

The oxime formation of aromatic aldehydes has directly been carried out with hydroxylamine hydrochloride using heteropoly acids (AlPW12O 40, AlPMo12O40) as catalysts in the absence of solvent. It is found that these heteropoly acids were effective catalysts for the formation of oxime of aldehydes. This method consistently has the advantage of high yields of the products, short reaction time, mild and solvent-free conditions, cleaner reactions and isolation procedures.

Alumina sulfuric acid mediated solvent-free and one-step Beckmann rearrangement of ketones and aldehydes and a useful reagent for synthesis of keto- and ald-oximes

Under solvent-free conditions, one-step Beckmann rearrangement of a variety of ketones and aldehydes could proceed in the presence of alumina sulfuric acid (ASA). The ASA reagent can also be used for the preparation of keto- and ald-oximes.

P2O5/SiO2 as an efficient reagent for the preparation of Z-aldoximes under solvent-free conditions

A facile and efficient method for the preparation of Z-aldoximes is improved by means of P2O5/SiO2 reagent in solvent-free media. Advantages of this method are the use of inexpensive and selective reagent, with high yields in simple operation, and short reaction time under solvent-free conditions. Copyright Taylor & Francis Inc.

Titanium oxide (TiO2) catalysed one-step Beckmann rearrangement of aldehydes and ketones in solvent free conditions

In the presence of titanium oxide (TiO2) and without any additional organic solvents, Beckmann rearrangement of several ketones and aldehydes was performed in good yield.

Solvent-free and one-step Beckmann rearrangement of ketones and aldehydes by zinc oxide

In the presence of zinc oxide and without any additional organic solvents, Beckmann rearrangement of several ketones and aldehydes were performed in good yields.

X=Y-ZH systems as potential 1,3-dipoles. Part 56: Cascade 1,3-azaprotio cyclotransfer-cycloaddition reactions between aldoximes and divinyl ketone: The effect of oxime E/Z isomerism on cycloaddition stereoselectivity

The cascade 1,3-azaprotiocyclotransfer (1,3-APT)-1,3-dipolar-cycloaddition (1,3-DC) reaction between aldoximes and divinyl ketone affords mixtures of exo and endo-isomers of substituted 1-aza-7-oxabicyclo[3.2.1]octan-4-ones, the ratio of which is dependent on the E/Z geometry of the starting oxime and its ability to isomerise under the thermal reaction conditions.