371944-56-8

Basic information

• Product Name: 2-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
• Synonyms: 2-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
• CAS NO: 371944-56-8
• Molecular Weight: 279.322
• Mol File: 371944-56-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one(371944-56-8)
• EPA Substance Registry System: 2-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one(371944-56-8)

Safety Data

• Hazardous Substances Data: 371944-56-8(Hazardous Substances Data)

Upstream product

• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 100-47-0 benzonitrile 
• 52505-46-1 ethyl 3-aminothieno[2,3-b]pyridine-2-carboxylate 
• 98-88-4 benzoyl chloride 
• 371943-39-4 C₁₅H₁₀N₂O₃S 
• 371943-54-3 C₁₇H₁₄N₂O₃S 
• 371943-98-5 C₁₅H₁₁N₃O₂S 

Relevant articles and documents

GLUCOSE UPTAKE INHIBITORS AND USES THEREOF

The present invention relates to novel compounds that modulate cellular glucose uptake by affecting various targets, including, but not limited to those related to glycolysis and known transporters/co-transporters of the GLUT family. The compounds according to the invention are useful for treating cancer such as: neuroendrocrine neoplasms, gastrointestinal stromal tumors (GIST), renal cell carcinoma, paraganglioma, pheochromocytoma, pituitary adenoma, colorectal cancer, lung cancer, gastric cancer, pancreatic cancer sarcoma, head and neck cancer, melanoma, ovarian cancer and other cancers that rely on high levels of glycolysis for survival and proliferation; as well as in treating of autoimmune diseases, inflammation, infectious diseases, and metabolic diseases.