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7-benzyl-1,3-dichloro-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

372090-70-5

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  • 7-benzyl-1,3-dichloro-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile

    Cas No: 372090-70-5

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372090-70-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 372090-70-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,2,0,9 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 372090-70:
(8*3)+(7*7)+(6*2)+(5*0)+(4*9)+(3*0)+(2*7)+(1*0)=135
135 % 10 = 5
So 372090-70-5 is a valid CAS Registry Number.

372090-70-5Relevant articles and documents

New heterocyclic systems derived from pyridine: New substrates for the investigation of the azide/tetrazole equilibrium

Sirakanyan, Samvel N.,Spinelli, Domenico,Geronikaki, Athina,Hovakimyan, Anush A.,Noravyan, Azat S.

, p. 8648 - 8656 (2014/12/10)

By exploiting the reactivity of 7-alkyl-3-chloro-4-cyano-1-hydrazino-5,6,7,8-tetrahydro-2,7-naphthyridines 5 some 7-alkyl-1-azido-3-chloro-4-cyano-5,6,7,8-tetrahydro-2,7-naphthyridines 6 were synthesized. Looking at their chemical properties we have ascer

KINASE INHIBITORS

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, (2013/09/26)

The present invention relates to compounds of formulae I and II wherein the variables are as defined herein. These compounds are capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.

METHOD OF TREATING CONDITIIONS WITH KINASE INHIBITORS

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Paragraph 0429-0430, (2013/09/26)

The present invention relates to a method of treating ophthalmic diseases and conditions, e.g. diabetic retinopathy, age-related macular degeneration, retinopathy of prematurity, etc., in a subject comprising administering to said subject a therapeutically effective amount of at least one compound of formula I or a prodrug, pharmaceutically acceptable salt, racemic mixtures or enantiomers of said compound. The compounds of formula I are capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.

Synthesis of 7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine and its analogs as bombesin receptor subtype-3 agonists

Guo, Cheng,Guzzo, Peter R.,Hadden, Mark,Sargent, Bruce J.,Yet, Larry,Kan, Yanqing,Palyha, Oksana,Kelly, Theresa M.,Guan, Xiaoming,Rosko, Kim,Gagen, Karen,Metzger, Joseph M.,Dragovic, Jasminka,Lyons, Kathryn,Lin, Linus S.,Nargund, Ravi P.

scheme or table, p. 2785 - 2789 (2010/07/08)

The original structure of a high-throughput screening hit obtained from an external vendor was revised based on multiple NMR studies. The active compound was re-synthesized via a novel route and its structure and biological activity as a BRS-3 agonist were unambiguously confirmed. Multi-gram quantities of the hit were prepared for pharmacokinetic and efficacy studies. The synthetic strategy allowed for the preparation of multiple analogs for SAR exploration.

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