372147-49-4

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL IMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLATE 98 is used as a chemical compound in drug discovery and development for its potential therapeutic properties. Its unique molecular structure allows it to be a candidate for the treatment of various medical conditions.
Used in Drug Development:
In the drug development process, ETHYL IMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLATE 98 is used as a starting material or intermediate in the synthesis of new pharmaceuticals, aiming to create medications with improved efficacy and safety profiles.
Used in Research and Development:
In research and development labs, ETHYL IMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLATE 98 is utilized as a research tool to study its pharmacological effects and explore its potential applications in treating different medical conditions.

InChI:InChI=1/C10H10N2O2/c1-2-14-10(13)8-3-5-12-6-4-11-9(12)7-8/h3-7H,2H2,1H3

Upstream product

• 107-20-0 2-chloroethanal 
• 13362-30-6 2-amino-4-ethoxycarbonyl-pyridine 
• 64-17-5 ethanol 
• 421595-79-1 imidazo[1,2-a]pyridine-7-carbonyl azide 
• 6065-32-3 4-bromocrotonic ethyl ester 
• 10111-08-7 2-imidazolecarbaldehyde 
• 421595-78-0 imidazo[1,2-a]pyridine-7-carbohydrazide 

Downstream Products

• 342613-80-3 7-hydroxymethylimidazo[1,2-a]pyridine 
• 1186514-46-4 N₃-(imidazo[1,2-a]pyridin-7-ylmethyl)-N₅-isobutyl-N₅,4'-dimethylbiphenyl-3,5-dicarboxamide 
• 372147-64-3 (Z)-ethyl α-[(triphenylphosphoranylidene)amino]-β-(imidazo[1,2-a]piridin-7-yl)propenoate 
• 421595-87-1 N-(triphenyl-λ⁵-phosphanylidene)imidazo[1,2-a]pyridin-7-amine 
• 421595-81-5 imidazo[1,2-a]pyridin-7-amine 

Relevant academic research and scientific papers

Facile synthesis of imidazo[1,2-a]pyridines via tandem reaction

An efficient method for the synthesis of 5,6,7-trisubstituted imidazo[1,2-a]pyridines was developed. The products were obtained in good yields under mild conditions.

Aminoimidazo[1,2-a]pyridines: Regioselective synthesis of substituted imidazonaphthyridines, azacarbolines and cyclazines

In order to study the regioselectivity of thermal cyclocondensation, aminoimidazo[1,2-a]pyridines (AIP) 5a-e were prepared, further converted into iminophosphoranes 7a-e, and ultimately converted regioselectively in angular annulated imidazonaphthyridines (IN) 8a, 10a, 11a, 12a or linear annulated dipyridoimidazole (DPI) 17a. From 2-substituted derivative 23, the peri annulated product 24a was obtained. The starting amines 5a-f reacted with aldehydes to yield regioselectively IN 8a-c, 10a-c, 11a-c, 12a,b, DPI 16a-e, 17a-d and TIBO like structures (±)-13 and 24a-c, as proved by X-ray analysis. The 1,2- or 1,4-addition between amines and α,β-unsaturated aldehydes concerning the pyridine and imidazole moieties is discussed in the light of these results.

Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-α]pyridines

Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-α]pyridines was explored experimentally and theoretically using semiempirical AM1 and ab initio methods. A range of functionalized vinylic derivatives (azido, amino, and carbodiimide groups) were prepared for conversion into pyrroloazaindoles 19-22, imidazo[1,x]-; (x=5, 6, 7, 8), [2,6]-, and [2,7]naphthyridines 28-30, 35-38 by thermal reaction. In the case of vinylic groups in the 5 position, peri annulation also was observed. The experimental and theoretical data are compared and discussed.