374-46-9

Usage

Uses

Used in Pharmaceutical Industry:
1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique fluorinated structure contributes to the development of drugs with improved pharmacokinetic and pharmacodynamic properties, enhancing their efficacy and safety in medical applications.
Used in Agrochemical Industry:
In the agrochemical sector, 1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL is employed as a building block for the creation of novel agrochemicals. Its incorporation into these products can lead to more effective and environmentally friendly pesticides, herbicides, and other agricultural chemicals.
Used as a Solvent in Industrial Processes:
1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL is utilized as a solvent in a range of industrial processes due to its ability to dissolve a variety of substances. Its use in this capacity can improve the efficiency and effectiveness of various chemical reactions and manufacturing procedures.
Used in Organic Synthesis:
As a reagent in organic synthesis, 1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL is particularly valuable in the preparation of fluorinated compounds. Its unique properties enable the development of new materials and molecules with specialized characteristics for use in various industries and research applications.
Environmental Considerations:
Given its classification as a volatile organic compound (VOC), 1,1,1,2,2-PENTAFLUORO-3-METHYLBUTAN-3-OL can contribute to air pollution if released into the atmosphere. Therefore, it is crucial to implement proper handling and disposal methods to minimize its environmental impact and ensure sustainable chemical management.

InChI:InChI=1/C5H7F5O/c1-3(2,11)4(6,7)5(8,9)10/h11H,1-2H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 426-65-3 ethyl Pentafluoropropionate 
• 142-96-1 dibutyl ether 
• 422-64-0 pentafluoropropionic acid 
• 378-75-6 perfluoropropionic acid methyl ester 
• 67-64-1 acetone 
• 56184-59-9 (pentafluoro ethyl) magnesiumbromide 

Relevant academic research and scientific papers

Estimation of hydrocarbon solubilities in hydrofluorocarbons

A new solubility parameter, SP, for hydrofluorocarbons (HFCs) has been developed (SP = 1.175 ln(np) + 0.025H - 0.063F - 0.028α - 0.018β where np depends on the molar volume and the molar refractivity; H and F are the number of hydrogens and fluorines, respectively, in the molecule; and α and β are the respective numbers of H-C-F and H-C-C-F connections).Values of SP have been used to predict if an HFC would be a good solvent for various hydrocarbons at 25 deg C.Within an isomeric HFC family, the individual HFCs having the greatest solvency for hydrocarbons were those having the maximum separation of fluorines from hydrogens.Hildebrand solubility parameters, δ, are compared with the semi-empirical SP values.Syntheses for 10 new compounds are given: 3,3,4,4,5,5,6,6,7,7-decafluorononane, 1,1,1,2-tetrafluoro-2-(trifluoromethyl)-3-methylbutane, 1,1,1,2,2-pentafluoro-3-methylbutane, 1,1,1,2,2,3,3,4,4-nonafluoro-5-methylhexane, 1,1,1,2,2,3,3,4,4-nonafluoroheptane, 1,1,1,2-tetrafluoro-2-(trifluoromethyl)butane, 1,1,1-trifluoro-3-(trifluoromethyl)butane, 1,1,1,2,2,3,3,5-octafluorohexane, 1,1,1,2,2-pentahydroperfluorooctane and 1,1,1,2,2-pentahydroperfluorodecane.