37460-51-8

Upstream product

• 106-93-4 ethylene dibromide 
• 95-55-6 2-amino-phenol 
• 124-38-9 carbon dioxide 
• 107-06-2 1,2-dichloro-ethane 

Downstream Products

• 220931-90-8 N,N'-dibenzyl-N,N'-bis(2-hydroxyphenyl)-1,2-diaminoethane 
• 220931-93-1 N,N'-bis(4-tert-butylbenzyl)-N,N'-bis(2-hydroxyphenyl)-1,2-diaminoethane 
• 220931-91-9 N,N'-bis(2-hydroxyphenyl)-N,N'-bis(4-methylbenzyl)-1,2-diaminoethane 
• 220931-92-0 N,N'-bis(4-chlorobenzyl)-N,N'-bis(2-hydroxyphenyl)-1,2-diaminoethane 
• 123641-26-9 N,N'-dimethyl-N,N'-bis(2-hydroxyphenyl)-1,2-diaminoethane 
• 744232-84-6 N,N'-[1,2-ethane-bis[2-phenyl-(benzoxazaborolidine)]] 
• 119150-02-6 1,2-bis-(2-acetoxy-N-acetyl-anilino)-ethane 
• 103155-82-4 1,2-bis-(N-acetyl-2-hydroxy-anilino)-ethane 

Relevant academic research and scientific papers

Synergetic activation of CO2by the DBU-organocatalyst and amine substrates towards stable carbamate salts for synthesis of oxazolidinones

The development of an efficient methodology to transform CO2 into valuable chemicals has attracted increasing attention concerning the challenging issues of CO2-utilization. Herein, an efficient approach for the preparation of oxazolidinones from CO2, primary (aliphatic/aromatic) amines and 1,2-dichloroethane (or its derivatives) catalyzed by DBU organo-superbase was achieved with yields of 47-97% under mild conditions (80-100 °C, 12 h, 1.0 MPa CO2). Control experiments demonstrated that the formation of an ion-pair carbamate salt intermediate IS-B derived from the reaction of CO2, DBU (catalyst) and an amine (substrate) was the key step for this three-component reaction. The available DBU-amine-CO2 adduct intermediate (like IS-B-2) with fair stability will evolve into the thermodynamically stable product oxazolidinones upon attack of 1,2-dichloroethane (or its derivatives), along with the regeneration of the DBU catalyst. Alternatively, the decomposition of the DBU-aryl amine-CO2 adduct (like IS-B-1) with relatively poor stability also could result in the competitive substitution reaction of 1,2-dichloroethane (or its derivatives) with the aryl amine. This work provides insights into synergetic CO2-activation by the DBU-catalyst and a nucleophilic amine-substrate via the formation of robust carbamate salt intermediates responsible for the final production of oxazolidinones. This journal is

Iron(II) complexes with tetradentate bis(aminophenolate) ligands: Synthesis and characterization, solution behavior, and reactivity with O2

Tetradentate bis(aminophenolate) ligands H2salanX and H2bapenX (where X refers to the para-phenolate substituent = H, Me, F, Cl) react with [Fe{N(SiMe3)2} 2] to form iron(II) com

Facile synthesis of 1,3,6-oxadiazepines from 2,2′-(1,2-ethanediyldiimino)bisphenols

A useful sequence of reactions for the syntheses of a variety of heterocyclic systems including an oxadiazepine ring is described. The key step involves the condensation of substituted 2,2′-(1,2-ethanediyldiimino)bisphenols with ethanedial to provide stereoselectively the 6a,7a-trans-6,6a,7a,8,15,16-hexahydro[1,4]benzoxazine[4′,3′:6,7] [1,3,6]oxadiazepino[2,3-c][1,4]-benzoxazine-6,8-diol framework, as established by X-ray diffraction analyses.