375-82-6

Basic information

• Product Name: 1H,1H-PERFLUORO-1-HEPTANOL
• Synonyms: 6:1 FTOH;1H,1H-PERFLUOROHEPTAN-1-OL;1H,1H-PERFLUOROHEPTANOL;1H,1H-PERFLUORO-1-HEPTANOL;1H,1H-TRIDECAFLUORO-1-HEPTANOL;2,2,3,3,4,4,5,5,6,6,7,7,7-TRIDECAFLUORO-1-HEPTANOL;Perfluoroheptanol;2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptan-1-ol
• CAS NO: 375-82-6
• Molecular Formula: C₇H₃F₁₃O
• Molecular Weight: 350.08
• EINECS: 206-796-8
• Product Categories: Fluorous Chemistry;Fluorous Compounds;Synthetic Organic Chemistry
• Mol File: 375-82-6.mol

Chemical Properties

• Boiling Point: 147 °C
• Flash Point: 37.3 °C
• Appearance: /
• Density: 1.75
• Vapor Pressure: 2.86mmHg at 25°C
• Refractive Index: 1.3020-1.3050
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 12.83±0.10(Predicted)
• Stability: Volatile
• CAS DataBase Reference: 1H,1H-PERFLUORO-1-HEPTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1H,1H-PERFLUORO-1-HEPTANOL(375-82-6)
• EPA Substance Registry System: 1H,1H-PERFLUORO-1-HEPTANOL(375-82-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-28-24/25-23
• HazardClass: IRRITANT
• Hazardous Substances Data: 375-82-6(Hazardous Substances Data)

Usage

Uses

Used in Microemulsion Stabilization:
1H,1H-Perfluoro-1-heptanol is used as a stabilizing agent for water-in-CO2 microemulsions due to its long multi-fluorocarbon-tail surfactants. These surfactants enhance the stability of the microemulsions, making it a valuable reagent in various applications where such stability is required.
Used in Chemical Industry:
In the chemical industry, 1H,1H-Perfluoro-1-heptanol is used as a reagent for stabilizing water-in-CO2 microemulsions, which can be crucial in various chemical processes and reactions. Its ability to stabilize these microemulsions contributes to improved efficiency and control in the chemical production process.
Used in Pharmaceutical Industry:
The pharmaceutical industry may also benefit from the use of 1H,1H-Perfluoro-1-heptanol as a stabilizing agent in the formulation of drug delivery systems. Its stabilizing properties can help improve the performance and effectiveness of certain medications, particularly those that require precise control over the release and distribution of active ingredients.
Used in Environmental Applications:
1H,1H-Perfluoro-1-heptanol can be employed in environmental applications, such as the remediation of contaminated sites or the treatment of wastewater. Its ability to stabilize water-in-CO2 microemulsions can be utilized to enhance the separation and removal of pollutants, contributing to a cleaner and more sustainable environment.

InChI:InChI=1/C7H3F13O/c8-2(9,1-21)3(10,11)4(12,13)5(14,15)6(16,17)7(18,19)20/h21H,1H2

Upstream product

• 75-89-8 2,2,2-trifluoroethanol 
• 559-14-8 perfluorooct-1-ene 
• 309260-93-3 3,3,5-trifluoro-5-tridecafluorohexyl-1,2,4-trioxolane 
• 41430-70-0 ethyl ester of perfluoropelargonic acid 
• 52447-22-0 perfluoroheptanoyl chloride 
• 14312-89-1 methyl perfluoroheptanoate 
• 375-85-9 perfluoroheptanoic acid 

Downstream Products

• 559-11-5 1,1-dihydroperfluoroheptyl acrylate 
• 129086-12-0 (2-{2-[2-(2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptyloxy)-ethoxy]-ethoxy}-ethoxymethyl)-benzene 
• 129086-13-1 [2-(2-{2-[2-(2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxymethyl]-benzene 
• 129086-14-2 {2-[2-(2-{2-[2-(2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxymethyl}-benzene 
• 129086-15-3 (2-{2-[2-(2-{2-[2-(2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxymethyl)-benzene 
• 48076-44-4 1H,1H-tridecafluoroheptyl methacrylate 
• 93764-89-7 2-(2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptyloxycarbonyl)-propane-1-sulfonatebenzyl-triethyl-ammonium; 
• 64739-16-8 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptane-1,1-diol 
• 1420073-12-6 C₂₁H₈F₂₆O₄ 
• 1420073-11-5 C₂₂H₁₀F₂₆O₄ 
• 1420073-08-0 C₂₁H₈F₂₆O₃ 
• 183997-47-9 1-Nitro-4-(2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-heptyloxy)-benzene 

Relevant articles and documents

METHOD OF PRODUCING FLUORINE-CONTAINING CARBONIC ACID ESTER

PROBLEM TO BE SOLVED: To provide a novel method of producing a fluorine-containing carbonic acid ester. SOLUTION: In a method of producing a fluorine-containing carbonic acid ester, a compound represented by formula (A1), a compound represented by formula (A2) and carbon dioxide are reacted in the presence of a base thereby producing a fluorine-containing carbonic acid ester represented by formula (A3), where formula (A1) is Ra1-OH, formula (A2) is Ra2-CHRa3-Lv, and formula (A3) is Ra1-O-CO-O-CHRa3-Ra2. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

Thermal desulfurization of (Alkoxymethyl)thiiranes

Reaction of (alkoxymethyl)oxiranes with thiourea in methanol has afforded the corresponding thiiranes, and catalyst-free thermal desulfurization of the products has been studied. The major products of desulfurization are alcohols and alkenes, both in the cases of (polyfluoroalkyloxymethyl)thiiranes and their non-fluorinated analogs. Longer alkyl chain in thiiranes favors formation of alcohols over alkenes formation in the course of desulfurization.

Ozonolysis of alkenes and studies of reactions of polyfunctional compounds: LXV.* Ozonolysis of perfluoro-1-octene in Freon-113

Ozonization of perfluoro-1-octene in Freon-113 yields the corresponding ozonide whose catalytic hydrogenation over Pd/C or hydride reduction leads to formation of perfluoroheptanoic acid; the reduction with lithium aluminum hydride gives 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-1-heptanol. Ozonization of perfluoro-1-octene in Freon-113 containing excess (≥3 equiv) alcohol affords the corresponding perfluoroheptanoic acid ester.

Process for functionalizing perfluorohalogenoalkanes

The present invention relates to the process of preparing perfluoro functional compounds from a perfluorohalogenoalkane having the general formula: wherein RF is a saturated, unsaturated, straight, or branched chain perfluoroalkyl radical containing 2 to 12 carbon atoms, and X is selected from chlorine, bromine, or iodine, comprising reacting said perfluorohalogenoalkane with a functionalizing reagent in the presence of a metallic couple dispersed in a sulfoxide-type solvent, said metallic couple having the general formula: wherein M1 is metal selected from Group IB, IIA, IIB, or IIIA of the Periodic Table and M2 is a metal having an electrochemical potential such that it can be deposited on metal M1.