37549-90-9Relevant academic research and scientific papers
Regio- and Stereo-selective γ-Substitution of Allylic Sulphoxides and Sulphones with Lithium Dialkylcuprates. A New Synthesis of Trisubstituted Olefins
Masaki, Yukio,Sakuma, Kazuhiko,Kaji, Kenji
, p. 434 - 435 (1980)
A new regio- and stereo-selective γ-substitution of allylic sulphoxides and sulphones with lithium dialkylcuprates providing a promising new method for the preparation of trisubstituted olefins in particular is described.
Synthesis of Tetrahydroisoindolinones via a Metal-Free Dehydrogenative Diels-Alder Reaction
Xu, Wen-Lei,Tang, Lei,Ge, Chen-Yu,Chen, Jie,Zhou, Ling
supporting information, p. 2268 - 2273 (2019/04/10)
A metal-free dehydrogenative Diels-Alder reaction of substituted alkenes for the synthesis of tetrahydroisoindolinones has been exploited for the first time. This new method features functional group tolerance and broad substrate scope, providing an efficient access to biologically active tetrahydroisoindolinone skeletons with endo steroselectivity in good to excellent yields. (Figure presented.).
Cer(III)-chlorid-unterstuetzte nucleophile Addition von Organolithiumreagentien an α-Alkyl-β-ketophosphinoxide: eine neue Methode fuer die Synthese stereochemisch definierter trisubstituierter Olefine
Bartoli, Giuseppe,Marcantoni, Enrico,Sambri, Letizia,Tamburini, Monica
, p. 2163 - 2164 (2007/10/03)
Keywords: Alkene; Alkylierungen; Asymmetrische Synthesen; Cerverbindungen; Horner-Wittig-Reaktionen
Regio- and Stero-selective Desulphurizative γ-Substitution of α-Substituted β-Methylallyl Sulphoxides and Sulphones with Lithium Dialkylcuprates providing Trisubstituted Olefins
Masaki, Yukio,Sakuma, Kazuhiko,Kaji, Kenji
, p. 1170 - 1176 (2007/10/02)
α-Substituted β-methylallyl sulphoxides (2) and sulphones (3) undergo regio- and stereo-selective desulphurizative γ-substitution by the action of lithium dialkylcuprates in ether.The reaction provides a new method for the synthesis of trisubstituted E-ol
A General Olefin Synthesis
Wenkert, Ernest,Ferreira, Tamis W.
, p. 840 - 841 (2007/10/02)
The reaction between secondary Grignard reagents and alkylthioarenes or alkylthioalkenes in the presence of 1:1 nickel dichloride-triphenylphosphine causing the substitution of alkylthio-groups by hydrogen atoms, the nickel(0)-induced replacement of alkylthio-groups of the aforementioned sulfides by alkyl or aryl functions, and the observation of regiocontrol in the catalysed reactions of Grignard reagents with unsymmetrical 1,1-bis(alkylthio)alkenes have led to a scheme of general, regio-, and stereo-selective olefin synthesis.
