75593-22-5Relevant academic research and scientific papers
Prenyl and geranyl phenyl sulfone, a new carbon nucleophile for Mitsunobu-type alkylation
Uemoto, Kaori,Kawahito, Atsuko,Matsushita, Noriko,Sakamoto, Izumi,Kaku, Hiroto,Tsunoda, Tetsuto
, p. 905 - 907 (2007/10/03)
Cyanomethylenetrimethylphosphorane (CMMP), a new Mitsunobu reagent developed recently by the authors, mediated the alkylation of prenyl and geranyl phenyl sulfone with primary and secondary alcohols quite efficiently. Utilizing geranyl phenyl sulfone, norfaranal, an analog of the unique trail pheromone produced by Pharaoh's ant, was synthesized in a short number of steps.
Phase transfer catalysis (ptc): a convenient tool for generation and reactions of allyl sulphonyl carbanions
Jonczyk, Andrzej,Radwan-Pytlewski, Tadeusz
, p. 111 - 119 (2007/10/03)
Allyl sulphones la-d or le react with alkyl halides (RX) in the presence of concentrated aqueous NaOH solution and tetrabutylammonium bromide (TBAB) as a catalyst to give, with high yields, mono(2a-d) or di-alkylated (3e) products, respectively. Under the same conditions sulphone If forms mixtures of the products, the composition of which depends on the structure of RX and the RX:lf ratio. With a,cu-dibromo alkanes, sulphones la,d-f give rise to cyclic products (7a,d-f) with low to excellent yields. With 4-nitrofluorobenzene (in solid NaOH-DMSO system) or vinyl acetate (by PTC) sulphone la affords the products 2al3 and 9a, respectively.
Regio- and Stero-selective Desulphurizative γ-Substitution of α-Substituted β-Methylallyl Sulphoxides and Sulphones with Lithium Dialkylcuprates providing Trisubstituted Olefins
Masaki, Yukio,Sakuma, Kazuhiko,Kaji, Kenji
, p. 1170 - 1176 (2007/10/02)
α-Substituted β-methylallyl sulphoxides (2) and sulphones (3) undergo regio- and stereo-selective desulphurizative γ-substitution by the action of lithium dialkylcuprates in ether.The reaction provides a new method for the synthesis of trisubstituted E-ol
