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METHYL 2-BROMO-2,3,3,3-TETRAFLUOROPROPIONATE is a colorless liquid chemical compound with the molecular formula C4H4BrF4O2. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and is primarily utilized as a reagent for the introduction of the 2,2,2-trifluoroethyl group into various organic compounds.

378-67-6

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378-67-6 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
METHYL 2-BROMO-2,3,3,3-TETRAFLUOROPROPIONATE is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new and improved products in these fields.
Used in Fluorinated Polymer Production:
METHYL 2-BROMO-2,3,3,3-TETRAFLUOROPROPIONATE is used in the manufacturing of fluorinated polymers, which have a wide range of applications due to their unique properties, such as chemical resistance, thermal stability, and non-stick surfaces.
Used in Specialty Chemicals Production:
METHYL 2-BROMO-2,3,3,3-TETRAFLUOROPROPIONATE serves as a building block for the production of specialty chemicals, which are used in various industries for their specific properties and functions.
Used in Chemical Industry:
Due to its unique fluorinated structure, METHYL 2-BROMO-2,3,3,3-TETRAFLUOROPROPIONATE has diverse applications in the chemical industry, and is valued for its ability to introduce fluorine atoms into organic molecules, enhancing their properties and performance.

Check Digit Verification of cas no

The CAS Registry Mumber 378-67-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,7 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 378-67:
(5*3)+(4*7)+(3*8)+(2*6)+(1*7)=86
86 % 10 = 6
So 378-67-6 is a valid CAS Registry Number.

378-67-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-bromo-2,3,3,3-tetrafluoropropanoate

1.2 Other means of identification

Product number -
Other names methyl 2-bromotetrafluoropropionate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:378-67-6 SDS

378-67-6Relevant academic research and scientific papers

Pyrolytic decarboxylation of some derivatives of perfluorinated mono- and dicarboxylic acids

Lebedev,Berenblit,Starobin,Gubanov

, p. 1640 - 1645 (2007/10/03)

Pathways of pyrolysis of perfluorinated carboxylic acids are considered in relation to the structure of the acids and reaction conditions. The reaction mechanism is discussed.

Reactions involving hexafluoropropylene oxide: Novel ring opening reactions and resolution of a racemic mixture of a bromofluoro ester, ultrasound mediated Reformatsky reactions and stereoselectivity

Coe, Paul L.,Loehr, Marianne,Rochin, Christophe

, p. 2803 - 2811 (2007/10/03)

A novel ring opening reaction of hexafluoropropylene oxide (HFPO) 1 with lithium bromide/zinc bromide and subsequent reaction of the resulting acyl fluoride with primary and secondary alcohols gave bromofluoro esters 2, 3, 4 and 7. Reaction of the corresponding acyl fluoride with water leads to acid 9 which on treatment with dehydroabietylamine 10 gave the diastereomeric salt 11. Resolution of 11 and subsequent hydrolysis and esterification reactions led to enantiomerically pure ester 12. Reformatsky reactions with 2 were studied which gave the alcohols 6 and 5. A Reformatsky reaction of 12 with formaldehyde afforded an alcohol 13 which is indicated by NMR spectroscopy in the presence of a chemical shift reagent to have proceeded stereoselectively.

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