37832-55-6 Usage
Uses
Used in Pharmaceutical and Agrochemical Industries:
2,5-dihydro-5-oxo-1H-pyrazole-3-carboxylic acid is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals for its ability to form a wide range of derivatives with different therapeutic and pesticidal properties.
Used in Organic Synthesis:
In the field of organic synthesis, 2,5-dihydro-5-oxo-1H-pyrazole-3-carboxylic acid is used as a building block to create a variety of compounds with distinct properties, contributing to the development of new chemical entities.
Used in Research and Development:
2,5-dihydro-5-oxo-1H-pyrazole-3-carboxylic acid is employed as a chemical reagent in research and development, facilitating the synthesis of new compounds and aiding in the exploration of the compound's pharmacological properties.
Used in Drug Discovery:
2,5-dihydro-5-oxo-1H-pyrazole-3-carboxylic acid is utilized in drug discovery processes as a potential drug candidate, being studied for its pharmacological properties to identify its therapeutic potential in various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 37832-55-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,8,3 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 37832-55:
(7*3)+(6*7)+(5*8)+(4*3)+(3*2)+(2*5)+(1*5)=136
136 % 10 = 6
So 37832-55-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N2O3/c7-3-1-2(4(8)9)5-6-3/h1H,(H,8,9)(H2,5,6,7)
37832-55-6Relevant academic research and scientific papers
Method for preparing 5-amino-1,2-dihydropyrazole-3-one from orotic acid
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Paragraph 0028; 0029, (2016/11/21)
The invention discloses a method for preparing 5-amino-1,2-dihydropyrazole-3-one from orotic acid, belonging to the field of drug intermediate synthesis. The method comprises the following steps: reacting orotic acid serving as a raw material with hydrazine hydrate to generate 5-oxygen-2,5-dihydropyrazole-3-carboxylic acid; reacting 5-oxygen-2,5-dihydropyrazole-3-carboxylic acid with diphenylphosphoryl azide by taking triethylamine as alkali to cause Curtis rearrangement, and carrying out hydrolysis, so as to generate 5-amino-1,2-dihydropyrazole-3-one. According the method, the cheap and easily available natural substances are taken as the raw materials, no strong base is utilized, and by-products are safe; meanwhile, the process selection is reasonable, the facility requirement is low, the operation is simple, the yield is high, the total yield can reach 83%, and the production is easily enlarged; the method is applicable to the large-scale production of 5-amino-1,2-dihydropyrazole-3-one.
