28491-52-3 Usage
General Description
5-amino-1,2-dihydropyrazol-3-one is a chemical compound characterized by the presence of Nitrogen (N), Carbon (C), Hydrogen (H), and Oxygen (O) atoms. Its molecular formula is C3H5N3O. This substance belongs to a class of organic compounds known as aminopyrazolines, which contain a pyrazoline ring where the nitrogen atom is substituted with an amino group. 5-amino-1,2-dihydropyrazol-3-one is less commonly known but may appear in various chemical reactions or synthetic procedures. As of now, its specific applications or uses aren't widely discussed in scientific literature. It is extremely important to handle and use this chemical compound while following standard safety protocols meant for chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 28491-52-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,4,9 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 28491-52:
(7*2)+(6*8)+(5*4)+(4*9)+(3*1)+(2*5)+(1*2)=133
133 % 10 = 3
So 28491-52-3 is a valid CAS Registry Number.
28491-52-3Relevant articles and documents
Method for preparing 5-amino-1,2-dihydropyrazole-3-one from orotic acid
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Paragraph 0028; 0030, (2016/11/21)
The invention discloses a method for preparing 5-amino-1,2-dihydropyrazole-3-one from orotic acid, belonging to the field of drug intermediate synthesis. The method comprises the following steps: reacting orotic acid serving as a raw material with hydrazine hydrate to generate 5-oxygen-2,5-dihydropyrazole-3-carboxylic acid; reacting 5-oxygen-2,5-dihydropyrazole-3-carboxylic acid with diphenylphosphoryl azide by taking triethylamine as alkali to cause Curtis rearrangement, and carrying out hydrolysis, so as to generate 5-amino-1,2-dihydropyrazole-3-one. According the method, the cheap and easily available natural substances are taken as the raw materials, no strong base is utilized, and by-products are safe; meanwhile, the process selection is reasonable, the facility requirement is low, the operation is simple, the yield is high, the total yield can reach 83%, and the production is easily enlarged; the method is applicable to the large-scale production of 5-amino-1,2-dihydropyrazole-3-one.