3784-22-3

Basic information

• Product Name: 1,1,2-triphenylpropane-1,2-diol
• Synonyms: 1,1,2-triphenylpropane-1,2-diol
• CAS NO: 3784-22-3
• Molecular Weight: 304.389
• Mol File: 3784-22-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,1,2-triphenylpropane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,2-triphenylpropane-1,2-diol(3784-22-3)
• EPA Substance Registry System: 1,1,2-triphenylpropane-1,2-diol(3784-22-3)

Safety Data

• Hazardous Substances Data: 3784-22-3(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 98-86-2 acetophenone 
• 464-72-2 tetraphenylethane-1,2-diol 
• 917-64-6 methyl magnesium iodide 
• 60-29-7 diethyl ether 
• 5623-26-7 α-methylbenzoin 
• 4237-46-1 α-phenylbenzoin 
• 129263-06-5 (S)-2-hydroxy-1,2-diphenylpropan-1-one 
• 13448-80-1 methyl R-(-)-atrolactate 

Downstream Products

• 795-36-8 1,1,1-triphenylacetone 
• 3677-70-1 1,1,2-triphenylprop-1-ene 
• 94866-53-2 2,3,3-triphenyl-prop-2-en-1-ol 
• 115917-76-5 1,4,4,4-tetraphenyl-butane-1,3-dione 
• 112686-73-4 1,1,1-triphenyl-pentane-2,4-dione 
• 100001-92-1 2,3,3-Triphenyl-allylchlorid 
• 36504-01-5 α,α-Diphenylpropiophenone 

Relevant articles and documents

Light-enabled metal-free pinacol coupling by hydrazine

Efficient carbon-carbon bond formation is of great importance in modern organic synthetic chemistry. The pinacol coupling discovered over a century ago is still one of the most efficient coupling reactions to build the C-C bond in one step. However, traditional pinacol coupling often requires over-stoichiometric amounts of active metals as reductants, causing long-lasting metal waste issues and sustainability concerns. A great scientific challenge is to design a metal-free approach to the pinacol coupling reaction. Herein, we describe a light-driven pinacol coupling protocol without use of any metals, but with N2H4, used as a clean non-metallic hydrogen-atom-transfer (HAT) reductant. In this transformation, only traceless non-toxic N2 and H2 gases were produced as by-products with a relatively broad aromatic ketone scope and good functional group tolerance. A combined experimental and computational investigation of the mechanism suggests that this novel pinacol coupling reaction proceeds via a HAT process between photo-excited ketone and N2H4, instead of the common single-electron-transfer (SET) process for metal reductants.

Retropinacol/cross-pinacol coupling reactions - A catalytic access to 1,2-unsymmetrical diols

A new concept to access unsymmetrical 1,2-diols with high yields is reported. This new methodology is based on a retropinacol/cross-pinacol coupling process. This transformation is characterized by its operational simplicity and very mild reaction condi tions.