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Benzenemethanol, 4-methyl-α-(4-methylphenyl)-α-(trifluoromethyl)-, also known as 4-methylbenzenemethanol, 4'-methyl-α,α-bis(trifluoromethyl)-, is an organic compound with the chemical formula C16H15F3O. It is a derivative of benzyl alcohol, featuring a benzene ring with a methyl group at the 4-position, an α-(4-methylphenyl) group, and an α-(trifluoromethyl) group. Benzenemethanol, 4-methyl-a-(4-methylphenyl)-a-(trifluoromethyl)- is characterized by its unique structure, which includes a hydroxyl group attached to a benzene ring, and is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals. The presence of trifluoromethyl groups can significantly influence the compound's physical and chemical properties, such as its reactivity, stability, and lipophilicity.

379-20-4

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379-20-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 379-20-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,7 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 379-20:
(5*3)+(4*7)+(3*9)+(2*2)+(1*0)=74
74 % 10 = 4
So 379-20-4 is a valid CAS Registry Number.

379-20-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2,2-trifluoro-1,1-di-p-tolyl-ethanol

1.2 Other means of identification

Product number -
Other names 2,2,2-Trifluoro-1,1-di-p-tolyl-ethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:379-20-4 SDS

379-20-4Downstream Products

379-20-4Relevant academic research and scientific papers

METHOD FOR PRODUCING TRIFLUOROMETHYL GROUP-CONTAINING ALCOHOLS

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Paragraph 0060; 0063; 0064, (2018/04/10)

PROBLEM TO BE SOLVED: To provide a method for producing trifluoromethyl group-containing alcohols useful as synthetic intermediates for medicines and agrochemicals. SOLUTION: This invention relates to a method for producing trifluoromethyl group-containing alcohols expressed by a formula (2), comprising: making carbonyl compounds expressed by a formula (1) react with trifluoromethane in an organic solvent in the presence of polyvalent ethers and potassium tert-butoxide, or kalium hexamethyldisilazide. (R1 and R2 are each independently a phenyl group etc.; R2 may combine with R1, to form a ring, and both R1 and R2 are not hydrogen atoms). SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Flow trifluoromethylation of carbonyl compounds by Ruppert-Prakash reagent and its application for pharmaceuticals, efavirenz and HSD-016

Okusu, Satoshi,Hirano, Kazuki,Yasuda, Yoshimasa,Tokunaga, Etsuko,Shibata, Norio

, p. 82716 - 82720 (2016/11/11)

The Ruppert-Prakash reagent is the most powerful and well-documented reagent for trifluoromethylation. Despite its versatility, no general method exists for its use in a flow system. Here we report the first flow trifluoromethylation of carbonyl compounds

Substituent Effects on the Solvolysis of 1,1-Diphenyl-2,2,2-trifluoroethyl Tosylates: Comparison between Symmetrically Disubstituted and Monosubstituted Systems

Fujio, Mizue,Morimoto, Hiroshi,Kim, Hyun-Joong,Tsuno, Yuho

, p. 1403 - 1411 (2007/10/03)

The solvolysis rates of 1-(substituted phenyl)-1-phenyl-2,2,2-trifluoroethyl and 1,1-bis(substituted phenyl)-2,2,2-trifluoroethyl tosylates or bromides were conductimetrically measured at 25.0 °C in 80% aqueous ethanol. The substituent effects on these so

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