37936-65-5Relevant articles and documents
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Nelson,W.L. et al.
, p. 4907 - 4910 (1978)
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Asymmetric synthesis of aryloxypropanolamines via OsO4-catalyzed asymmetric dihydroxylation
Sayyed, Iliyas A.,Thakur, Vinay V.,Nikalje, Milind D.,Dewkar, Gajanan K.,Kotkar,Sudalai
, p. 2831 - 2838 (2007/10/03)
A simple and effective procedure for the enantioselective synthesis of several β-adrenergic blocking agents incorporating the first asymmetric synthesis of celiprolol, is described. The key steps are (i) sharpless asymmetric dihydroxylation of aryl allyl ethers to introduce chirality into the molecules and (ii) conversion of cyclic sulfates into the corresponding epoxides using a three-step procedure.
Enantioselective ring opening of epoxides with trimethylsilyl azide (TMSN3) in the presence of β-cyclodextrin: An efficient route to 1,2-azido alcohols
Kamal, Ahmed,Arifuddin,Rao, Maddamsetty V.
, p. 4261 - 4264 (2007/10/03)
The ring opening of epoxides with nucleophiles such as TMSN3 and isopropylamine takes place enantioselectively in the presence of β- cyclodextrin under extremely mild conditions and the azido alcohols and amino alcohols are formed as (S)-isomers. (C) 1999 Published by Elsevier Science Ltd.