55315-87-2Relevant academic research and scientific papers
Difluorocarbene induced of facile synthesis of chlorohydrins from glycidyl ethers
Singh, Sapna,Bhadury, Pinaki S.,Sharma, Mamta,Palit, Meehir,Jaiswal, Devendra K.
, p. 1249 - 1253 (2007/10/03)
A novel and unusual approach based on a ClCF2COONa-DMF system has been developed for the synthesis of chlorohydrins via an unexpected mechanism. In a first ever report for the synthesis of chlorohydrins from glycidyl ethers, e.g., CH2=CH-CH2-O-Z, CH 3CH2-O-Z, C6H5-O-Z, C 6H4(o-CH3)-O-Z, CH2=C(CH 3)C(=O)-O-Z, etc., (where Z = glycidyl), difluorocarbene-induced facile regioselective ring opening of epoxides has generated the compound in high yield (70%-83%).
Highly stereoselective reduction of haloketones using three new yeasts: Application to the synthesis of (S)-adrenergic β-blockers related to propranolol
Martinez Lagos, Fernando,Carballeira, Jose D.,Bermudez, Jose L.,Alvarez, Emilio,Sinisterra, Jose V.
, p. 763 - 770 (2007/10/03)
The stereoselective reduction of aryloxy-halo-2-propanones 1 or of 1-chloro-3(phthalimdyl)-propan-2-one 2 using baker's yeast usually displays poor yields and/or ees. Three new yeasts, Saccharomyces bayanus CECT 1317, Yarrowia lipolytica CECT 1240 and Pic
