37985-18-5

Basic information

• Product Name: 2-Thiocyanato-2-methylpropane
• Synonyms: 2-Thiocyanato-2-methylpropane
• CAS NO: 37985-18-5
• Molecular Formula: C₅H₉NS
• Molecular Weight: 115.2
• Mol File: 37985-18-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 10.5°C
• Boiling Point: 140°C (rough estimate)
• Appearance: /liquid
• Density: 0.919
• Refractive Index: 1.5005 (estimate)
• CAS DataBase Reference: 2-Thiocyanato-2-methylpropane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiocyanato-2-methylpropane(37985-18-5)
• EPA Substance Registry System: 2-Thiocyanato-2-methylpropane(37985-18-5)

Safety Data

• Hazardous Substances Data: 37985-18-5(Hazardous Substances Data)

Upstream product

• 60-29-7 diethyl ether 
• 463-56-9 thiocyanic acid 
• 115-11-7 isobutene 
• 507-19-7 t-butyl bromide 
• 557-42-6 zinc(II) thiocyanate 
• 507-20-0 tertiary butyl chloride 
• 2092-17-3 barium thiocyanate 
• 333-20-0 potassium thioacyanate 

Relevant articles and documents

Support-controlled Switching of Sulphur-Nitrogen Nucleophilicity for Inorganic Solid-supported Alkaline Earth Metal Thiocyanate Reagents

A dramatic change in the sulphur-nitrogen selectivity of the SCN substitution of t-butyl bromide was observed, in addition to a dramatic increase in reaction rate, by simply supporting various alkaline earth metal thiocyanates on various inorganic solids.

Microwave-assisted synthesis of alkyl thiocyanates

Microwave irradiation accelerated the reaction of t-alkyl, allyl, and benzyl halides with Zn(SCN)2 to afford thiocyanates in excellent yields and high selectivity with the formation of isothiocyanates only in minor proportions. Because thiocyanates are stable intermediates to thiols, the method also affords facile access to corresponding thiols.

Nucleophilic substitution of S(N)1-active halides using zinc salts: preparation of thio- and isothiocyanates

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