37993-32-1

Basic information

• Product Name: H-ACH-OME
• Synonyms: H-ACH-OME;1-Amino-1-cyclohexanecarboxylic acid methyl ester hydrochloride;Methyl 1-aminocyclohexanecarboxylate HYDROCHLORIDE Salt;Methyl 1-Aminocyclohexanecarboxylate HCl
• CAS NO: 37993-32-1
• Molecular Formula: C₈H₁₅NO₂*ClH
• Molecular Weight: 193.67114
• Mol File: 37993-32-1.mol
• Article Data: 17

Chemical Properties

• Melting Point: 210-212 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7))
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: H-ACH-OME(CAS DataBase Reference)
• NIST Chemistry Reference: H-ACH-OME(37993-32-1)
• EPA Substance Registry System: H-ACH-OME(37993-32-1)

Safety Data

• Hazardous Substances Data: 37993-32-1(Hazardous Substances Data)

Usage

General Description

"H-ACH-OME" refers to a combination of chemicals that include hydrochloric acid (HCl), acetic acid (CH3COOH), hydrogen peroxide (H2O2), and a variety of minerals and enzymes. Hydrochloric acid is a strong acid that is used in various industrial processes and as a cleaning agent. Acetic acid is a weak acid commonly found in vinegar and is used in food production and as a solvent. Hydrogen peroxide is a bleaching agent and disinfectant that is used in various applications, from hair and skin products to industrial cleaning and water treatment. The combination of these chemicals and minerals provides a potent solution for cleaning and disinfecting various surfaces and materials.

Upstream product

• 2756-85-6 1-aminocyclohexane carboxylic acid 
• 75-36-5 acetyl chloride 
• 108-94-1 cyclohexanone 
• 702-62-5 spiro(imidazolidine-4,1'-cyclohexane)-2,5-dione 
• 67-56-1 methanol 

Downstream Products

• 139456-17-0 2-Acetyl-4-(4-chloro-phenyl)-1,3,4-triaza-spiro[5.5]undec-2-en-5-one 
• 174077-47-5 Boc-Phe-Ac₆c-OMe 
• 871828-14-7 methyl 1-(4-bromobenzoylamino)cyclohexanecarboxylate 
• 957122-16-6 methyl 1-{[2-[(tert-butoxycarbonyl)amino]-2-(3,5-difluorophenyl)propyl]amino}cyclohexane-1-carboxylate 
• 287407-13-0 methyl 1-({[4-(2-butynyloxy)phenyl]sulfonyl}amino)cyclohexanecarboxylate 
• 1311295-63-2 C₂₁H₃₄N₂O₄Si 
• 1311295-17-6 C₁₄H₁₇N₃O₅ 
• 1311295-16-5 C₁₅H₂₀N₂O₄ 

Relevant articles and documents

Microwave-Assisted Ruthenium- and Rhodium-Catalyzed Couplings of α-Amino Acid Ester-Derived Phosphinamides with Alkynes

Two different types of new phosphinamide α-amino ester derivatives have been prepared in moderate to high yields via ruthenium(II) and rhodium(III)-catalyzed ortho-C?H functionalization under microwave irradiation. Specifically, the ortho-alkenylated phosphinamides were produced through coupling of phosphinamides containing an α-substituted or α,α-disubstituted α-amino ester with internal alkynes under ruthenium catalysis. In contrast, Ru and the more effective Rh-catalyzed coupling of the α-unsubstituted glycine ester phosphinamide with alkynes resulted in formation of oxidative annulation products, phosphaisoquinolin-1-ones. The developed methods feature the use of easily accessible starting materials, short reaction time, exclusive E-stereoselectivity (for ortho-alkenylation) and good functional group tolerance. The alkenylation reaction was readily scaled up to gram scale. Furthermore, the obtained alkenylated phosphinamide could be transformed into P-containing dipeptides through hydrolysis of the ester group in the catalysis product and subsequent condensation with an α-amino ester.

A COMPOUND FOR INHIBITING 11BETA-HYDROXY STEROID DEHYDROGENASE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

Disclosed are a novel compound or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition including the same for inhibiting human 11-beta-hydroxy steroid dehydrogenase type 1 (11beta-HSD1). The disclosed compound and the pharmaceutical composition including the same for inhibiting human 11-beta-hydroxy steroid dehydrogenase type 1 (11beta-HSD1) are excellent in activity and solubility, and is more efficient in formulation and transfer.

5,6-BISARYL-2-PYRIDINE-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF AS UROTENSIN II RECEPTOR ANTAGONISTS

The present invention relates to 5,6-bisaryl-2-pyridinecarboxamides, to their preparation and to their therapeutic use as urotensin II receptor antagonists.