380-34-7Relevant academic research and scientific papers
Synthesis and use of partially fluorinated dialkyl ethers derived from hexafluoropropylene
Il'in,Bakhmutov,Ivanova,Furin,Tolstikova,Sukhinin
, p. 98 - 101 (2004)
A procedure was developed for preparing partially fluorinated dialkyl ethers by the reaction of hexafluoropropylene with aliphatic and polyfluorinated alcohols in the presence of KOH. On treatment with concentrated sulfuric acid, these ethers form alkyl esters of acids, and on treatment with KOH, alkenyl ethers.
Method for removing unsaturated impurities in 1, 1, 2, 3, 3 and 3 - hexafluoropropyl hydrofluoroether crude product
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Paragraph 0057-0064, (2021/10/27)
The invention provides a method of removing 1. [] The hydrofluoroether impurities, pentafluoropropylene hydrofluoroether, and, 1 1 pentafluoropropylene 2 hydrofluoroether 3 impurities 3 can 3 - be well separated to provide, hexafluoropropyl hydrofluoroether product 1 having a 1 2 purity of 3 3 - at least. 1 2 1, 2, 3, 3, 3 - 3 1 1 3 3 - 99% 3 3 - 2 3The method does not use dangerous chemical, greatly improves the operation safety, does not generate waste harmful to the environment, and can be regenerated and reused by the adsorbent silica gel column. Cost is reduced, and resources are saved.
Fluorine gas for life science syntheses: Green metrics to assess selective direct fluorination for the synthesis of 2-fluoromalonate esters
Harsanyi, Antal,Sandford, Graham
supporting information, p. 3000 - 3009 (2015/05/27)
Optimisation and real time reaction monitoring of the synthesis of 2-fluoromalonate esters by direct fluorination using fluorine gas is reported. An assessment of green metrics including atom economy and process mass intensity factors, demonstrates that the one-step selective direct fluorination process compares very favourably with established multistep processes for the synthesis of fluoromalonates.
Palladium(0)-catalyzed hydroalkoxylation of hexafluoropropene: Synthesis of hydrofluoroethers under neutral conditions
Matsukawa, Yasuhisa,Mizukado, Junji,Quan, Heng-Dao,Tamara, Masanori,Sekiya, Akira
, p. 1128 - 1130 (2007/10/03)
No vinyl ether by-products are formed in the palladium(0)-complex catalyzed hydroalkoxylation of hexafluoropropene (see scheme). Saturated hydrofluoro-ethers are selectively synthesized with alcohols or phenols under neutral conditions in the presence of
Transformation de l'hexafluoropropene en alcool trifluoroallylique, precurseur des α-fluoroacrylates
Nguyen, Thoai,Wakselman, Claude
, p. 273 - 278 (2007/10/03)
The fluoroacryloyl fluoride precursor of α-fluoroacrylic acid esters can arise from an allylic transposition of trifluoroallylic alcohol of which two methods of preparation are presented.In the first, dehydrofluoration of the alcohol CF3CFHCH2OH (4) is used.This alkohol is generated from the ester CF3CFHCOOC2H5 (3).In the second, dehalogenation of the alcohol CF3CFBrCH2OH (10) by zinc is used.The latter is formed by the selective reduction of the ester CF3CFBrCOOC2H5 (9). - Keywords: 2H-Tetrafluoropropanoic acid ester; 2H-Tetrafluoropropanol-1; Trifluoroallylic alcohol; α-Fluoroacryloyl fluoride; NMR spectroscopy
FACILE SYNTHESIS OF DIALKYL FLUOROMALONATES AND THEIR DERIVATIVES
Ishikawa, Nobuo,Takaoka, Akio
, p. 107 - 110 (2007/10/02)
Dimethyl and diethyl fluoromalonates were prepared by the stepwise basic alcoholysis of hexafluoropropene in a total yield of 50 - 55 percent.These dialkyl fluoromalonates were alkylated with alkyl halides, and the resulting dialkyl α-fluoroalkylmalonates were cyclized with urea affording 5-fluorobarbituric acid derivatives.
