380357-38-0

Usage

Uses

Used in Pharmaceutical Industry:
(R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE is used as a key intermediate for the development of various pharmaceutical compounds. Its unique structure and chirality allow for the creation of novel drugs with improved efficacy and selectivity, targeting specific biological pathways.
Used in Agrochemical Industry:
In the agrochemical sector, (R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE serves as a crucial building block for the synthesis of new agrochemicals. Its properties enable the development of innovative products with enhanced pest control capabilities and reduced environmental impact.
Used in Organic Synthesis:
(R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE is employed as a versatile building block in organic synthesis, allowing chemists to create a diverse range of compounds with potential applications in various industries, including materials science, chemical engineering, and biotechnology.
Used in Drug Discovery:
(R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE plays a significant role in drug discovery, as its unique structure and properties facilitate the development of new therapeutic agents. Researchers can leverage its chirality and reactivity to design and synthesize novel drug candidates with improved pharmacological profiles and targeted therapeutic effects.

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 163439-82-5 (3R,4R)-1-benzyl-3,4-pyrrolidinediol 
• 187032-53-7 (3S,4S)-1-N-benzyl-3,4-dihydroxypyrrolidine-2,6-dione 
• 100-46-9 benzylamine 

Downstream Products

• 193352-75-9 (3S,4S)-1-benzyl-pyrrolidine-3,4-diamine 
• 140134-20-9 (3R,4R)-3,4-diazido-1-benzylpyrrolidine 
• 288313-99-5 3,4-Diazido-1-benzylpyrrolidine 

Relevant academic research and scientific papers

Urea vs. carbamate groups: a comparative study in a chiral C2 symmetric organogelator

The effect of the replacement of molecular moieties (carbamates vs. urea) that drive self-assembly for two organogelators with an identical C2 symmetric molecular structure is described. The main properties of the gels obtained from the urea-ba

Synthesis of an ovoid chiral cage

Evidence for the formation of an ovoid chiral cage, resulting from the auto-assembly of two hexafunctional and three tetrafunctional modules reacting through dynamic covalent bond formation, is provided. Georg Thieme Verlag Stuttgart.

Substituted 3-Amino-Pyrrolidino-4-Lactams

The invention provides compounds of formula (1), and the pharmaceutically acceptable salt thereof, wherein R1, n and R2 are as described herein; compositions thereof; and uses thereof.

Enantioselective Catalysis, 4. Synthesis of N-Substituted (R,R)-3,4-Bis(diphenylphosphino)pyrrolidines. The Use of their Rhodium Complexes for the Asymmetric Hydrogenation of α-(Acylamino)acrylic Acid Derivatives

A simple synthesis of (R,R)-3,4-bis(diphenylphosphino)pyrrolidine (6a) and some N-substituted derivatives 6b-m is described. 6l and 6m are optically active tetraphosphanes, composed of two (R,R)-3,4-bis(diphenylphosphino)pyrrolidine units and a dicarboxylic residue.The structure of the parent compound 6a was determined by X-ray diffraction.From the phosphanes 6a-m the cationic 1,5-cyclooctadiene-bisphosphane-rhodium complexes 7a-m were prepared.The complexes 7l and 7m are ligand bridged bis(rhodium) dications.The complexes 7a-m were used for the asymmetric catalytic hydrogenation of the α-(acylamino)acrylic acid derivatives 9a-l.Enantiomeric excesses up to 100percent were achieved.Between 1 and 70 at the optical yields do not depend on the hydrogen pressure.The substrate/catalyst ratio can be as high as 50000/1.