3813-27-2

Basic information

• Product Name: 3-(DIETHYLAMINO)PROPANAMIDE
• Synonyms: 3-(DIETHYLAMINO)PROPANAMIDE
• CAS NO: 3813-27-2
• Molecular Formula: C₇H₁₆N₂O
• Molecular Weight: 144.21
• Mol File: 3813-27-2.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 266.3°C at 760 mmHg
• Flash Point: 114.9°C
• Appearance: /
• Density: 0.947g/cm³
• Vapor Pressure: 0.00871mmHg at 25°C
• Refractive Index: 1.461
• PKA: 16.37±0.40(Predicted)
• CAS DataBase Reference: 3-(DIETHYLAMINO)PROPANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(DIETHYLAMINO)PROPANAMIDE(3813-27-2)
• EPA Substance Registry System: 3-(DIETHYLAMINO)PROPANAMIDE(3813-27-2)

Safety Data

• Hazardous Substances Data: 3813-27-2(Hazardous Substances Data)

Usage

General Description

3-(Diethylamino)propanamide is a chemical compound with the molecular formula C8H18N2O. It is a secondary amine and an amide, with a structure consisting of a propyl group attached to a diethylamino group. 3-(DIETHYLAMINO)PROPANAMIDE is used in the synthesis of pharmaceuticals and organic materials, and it has a wide range of applications in the chemical industry. It is also used as a catalyst in organic reactions and as a reagent in research and development. 3-(Diethylamino)propanamide is an important building block for the production of various compounds and is commonly found in chemical supply stores for industrial and research purposes.

InChI:InChI=1/C7H16N2O/c1-3-9(4-2)6-5-7(8)10/h3-6H2,1-2H3,(H2,8,10)

Upstream product

• 109-89-7 diethylamine 
• 79-06-1 2-propenamide 
• 3840-67-3 sulfuric acid mono-(2-carbamoyl-ethyl) ester 
• 121-44-8 triethylamine 

Relevant articles and documents

Palladium-catalyzed C-N bond activation: The synthesis of β-amino acid derivatives from triethylamine and acrylates

In the palladium-catalyzed reaction of acrylates, C-N bond activation and acetalization occurred under different conditions. Described herein is a highly efficient palladium-catalyzed C-N bond activation reaction and subsequent new C-N bond formation to directly construct β-amino acids from triethylamine and acrylate esters in isolated yields of up to 95%. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.

On-water magnetic NiFe2O4 nanoparticle-catalyzed Michael additions of active methylene compounds, aromatic/aliphatic amines, alcohols and thiols to conjugated alkenes

Here, we have demonstrated the Michael addition of active methylene compounds, aromatic/aliphatic amines, thiols and alcohols to conjugated alkenes using magnetic nano-NiFe2O4 as reusable catalyst in water. Nano-NiFe2O4 efficiently catalyzed the formation of C-C and C-X (X = N, S, O etc.) bond through 1,4-addition reactions.

An efficient biomaterial supported bifunctional organocatalyst (ES-SO 3- C5H5NH+) for the synthesis of β-amino carbonyls

A biomaterial supported organocatalyst, readily synthesized by the reaction of chemically modified sulfonic group containing expanded corn starch with pyridine exhibited excellent catalytic activity for the synthesis of β-amino carbonyls in excellent yields via aza-Michael addition of amines to electron deficient alkenes. A remarkable enhancement in the reaction rates was observed with the prepared bifunctional organocatalyst in comparison to the either starch grafted sulfonic acid or the corresponding homogeneous pyridinium p-toluenesulfonate.