3814-25-3

Upstream product

• 92424-06-1 bis[4-(methanesulfonyl)phenyl] disulfide 
• 5470-49-5 4-methanesulfonylphenylamine 
• 140-89-6 potassium ethyl xanthogenate 
• 82964-91-8 4-methylsulfinylbenzenesulfonyl chloride 
• 701-57-5 1-methylthio-4-nitro-benzene 
• 3466-32-8 4-bromoohenyl methyl sulfone 
• 455-15-2 1-(methylsufonyl)-4-fluorobenzene 
• 98-57-7 4-chlorophenyl methyl sulfone 
• 1393937-27-3 4-(tert-butylthio)phenyl methyl sulfone 
• 91179-42-9 O-4-methylsulfonylphenyl dimethylthiocarbamate 
• 2976-30-9 1-methanesulfonyl-4-nitrobenzene 

Downstream Products

• 92424-06-1 bis[4-(methanesulfonyl)phenyl] disulfide 
• 86602-00-8 2,4-dinitro-4'-methylsulfonyldiphenyl sulfide 
• 52323-93-0 1-methanesulfonyl-4-methylsulfanyl-benzene 
• 874529-00-7 (4-methanesulfonyl-phenyl)-phenyl disulfide 
• 22218-65-1 4-Mesyl-phenylsulfonylmethylthiocyanat 
• 75317-07-6 2,4-dinitro-4'-methylsulfonyldiphenyl sulfone 
• 22821-86-9 1,4-bis(methanesulfonyl)benzene 
• 1393937-26-2 p-(methanesulfonyl)phenyl chlorotetrafluoride 
• 1375459-03-2 C₁₈H₁₉NO₆S₂ 
• 1206968-53-7 tert-Butyl 4-[2-(4-methanesulfonylphenylthiomethyl)-pyridin-5-yl]piperidine-1-carboxylate 
• 98190-66-0 <4-Methoxy-2-(4-methylsulfonylphenylthio)phenyl>acetic Acid 
• 98190-60-4 Ethyl 4-Methoxy-2-(4-methylsulfonylphenylthio)benzoate 
• 98190-64-8 <4-Methoxy-2-(4-methylsulfonylphenylthio)phenyl>acetonitrile 
• 98190-59-1 4-Methoxy-2-(4-methylsulfonylphenylthio)benzoyl Chloride 

Relevant academic research and scientific papers

Discovery of practical production processes for arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides): Beginning of a new era of "super-trifluoromethyl" arene chemistry and its industry

Various arylsulfur pentafluorides, ArSF5, have long been desired in both academic and industrial areas, and ArSF5 compounds have attracted considerable interest in many areas such as medicines, agrochemicals, and other new materials, since the highly stable SF5 group is considered a "super-trifluoromethyl group" due to its significantly higher electronegativity and lipophilicity. This article describes the first practical method for the production of various arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides), from the corresponding diaryl disulfides or aryl thiols. The method consists of two steps: (Step 1) treatment of a diaryl disulfide or an aryl thiol with chlorine in the presence of an alkali metal fluoride, and (step 2) treatment of the resulting arylsulfur chlorotetrafluoride with a fluoride source, such as ZnF2, HF, and Sb(III/V) fluorides. The intermediate arylsulfur chlorotetrafluorides were isolated by distillation or recrystallization and characterized. The aspects of these new reactions are revealed and reaction mechanisms are discussed. As the method offers considerable improvement over previous methods in cost, yield, practicality, applicability, and large-scale production, the new processes described here can be employed as the first practical methods for the economical production of various arylsulfur pentafluorides and their higher homologues, which could then open up a new era of "super-trifluoromethyl" arene chemistry and its applications in many areas.

GPCR AGONISTS

Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.

NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES

The present invention relates to a compound which has a glucokinase-activating effect and is useful as a therapeutic agent for diabetes mellitus, being represented by a formula (I): [wherein X1 represents a nitrogen atom, sulfur atom, oxygen at

NOVEL SUBSTITUTED 3-SULFUR INDOLES

The present invention relates to substituted indoles useful as pharmaceutical compounds for treating respiratory disorders.

NOVEL SUBSTITUTED INDOLES

The present invention relates to substituted indoles of formula (I) useful as pharmaceutical compounds for treating respiratory disorders.

New and more potent antifungal bisulfides

From a design principle described in an earlier paper, a new series of substituted aryl methyl disulfides have been prepared and tested against Aspergillus niger and Aspergillus flavus. Methyl p-nitrophenyl disulfide is more potent (by an order of magnitude) than the fungitoxic natural product (CH3SCH2S)2. With the present rationale in hand, one can anticipate which Polycarpamine is an effective antifungal agent. CSIRO 2000.

2,6-diaryl pyridazinones with immunosuppressant activity

A class of 2,6-diarylpyridazinones of general structural formula I have been identified that exhibit exhibit immunosuppressant activity with human T-lymphocytes, and are useful as an immunosuppressants. STR1 or a pharmaceutically acceptable salt, hydrate or crystal form thereof