38151-56-3

Basic information

• Product Name: 4,4-diphenylbutyraldehyde
• Synonyms: 4,4-diphenylbutyraldehyde
• CAS NO: 38151-56-3
• Molecular Weight: 224.302
• Mol File: 38151-56-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4,4-diphenylbutyraldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-diphenylbutyraldehyde(38151-56-3)
• EPA Substance Registry System: 4,4-diphenylbutyraldehyde(38151-56-3)

Safety Data

• Hazardous Substances Data: 38151-56-3(Hazardous Substances Data)

Upstream product

• 14578-67-7 4,4-diphenylbutanoic acid 
• 22156-48-5 3,3-diphenylpropionitrile 
• 41140-53-8 1-Methanesulfonyloxy-3,3-diphenylpropane 
• 23426-03-1 3,3-diphenylpropanoic acid methyl ester 
• 20017-67-8 3,3-diphenylpropan-1-ol 
• 606-83-7 3,3-Diphenylpropionic acid 
• 6078-95-1 4,4-diphenyl-3-butenyl bromide 
• 36265-55-1 1,1-diphenyl-4-bromobutane 
• 56740-71-7 4,4-diphenyl-1-butanol 

Downstream Products

• 134420-92-1 ethyl 6,6-diphenyl-2-hexenoate 
• 132287-50-4 2-bromo-4,4-diphenylbutanal 
• 102390-63-6 4⁽⁵⁾-(2,2-Diphenylethyl)imidazole 
• 169756-89-2 (2S,4S)-4-(4,4-Diphenyl-butyl)-5-oxo-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 
• 164300-34-9 [2-(3,3-diphenyl-propyl)-[1,3]dioxolan-4-ylmethyl]-dimethyl-amine 
• 169756-84-7 (2S, E)-1-(tert-Butoxycarbonyl)-4-(4,4-diphenylbutylidene) pyroglutamate ethyl ester 
• 169756-85-8 (2S, Z)-1-(tert-Butoxycarbonyl)-4-(4,4-diphenylbutylidene) pyroglutamate ethyl ester 

Relevant articles and documents

Metal-Free Enantioselective Oxidative Arylation of Alkenes: Hypervalent-Iodine-Promoted Oxidative C?C Bond Formation

The enantioselective oxyarylation of (E)-6-aryl-1-silyloxylhex-3-ene was achieved using a lactate-based chiral hypervalent iodine(III) reagent in the presence of boron trifluoride diethyl etherate. The silyl ether promotes the oxidative cyclization, and enhances the enantioselectivity. In addition, the corresponding aminoarylation was achieved.

GABA-uptake inhibitors: Construction of a general pharmacophore model and successful prediction of a new representative

A model for the pharmacophore of GABA-uptake inhibitors was established using published structure-activity data and molecular modeling. The model accounted for the activities of different classes of GABA-uptake inhibitors. Analogues of guvacine substituted at position 6 were synthesized in order to confirm the model. 6-(3,3-Diphenylpropyl)guvacine (30f), which fit well with the pharmacophore, had an in vitro IC50 of 0.1 μM. This value is as good as those of the best GABA-uptake inhibitors known today.