38239-32-6

Basic information

• Product Name: 5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester
• Synonyms: 2-Bromo-5-methoxycarbonyl-3-nitrothiophene;5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester;2-Thiophenecarboxylic acid, 5-bromo-4-nitro-, methyl ester (7CI,9CI);methyl 5-bromo-4-nitrothiophene-2-carboxylate;5-broMo-4-nitro-;methyl 5-bromo-4-nitrothiophene-
• CAS NO: 38239-32-6
• Molecular Formula: C₆H₄BrNO₄S
• Molecular Weight: 266.08
• Product Categories: API intermediates
• Mol File: 38239-32-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 324.1°Cat760mmHg
• Flash Point: 149.8°C
• Appearance: /
• Density: 1.837g/cm³
• Vapor Pressure: 0.000251mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester(38239-32-6)
• EPA Substance Registry System: 5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester(38239-32-6)

Safety Data

• Hazardous Substances Data: 38239-32-6(Hazardous Substances Data)

Usage

General Description

5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester is a chemical compound with the molecular formula C7H5BrN2O4S. It is a methyl ester derivative of 5-bromo-4-nitrothiophene-2-carboxylic acid and is commonly used in various organic synthesis and pharmaceutical research applications. 5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester is known to possess diverse biological activities, including antimicrobial and anticancer properties, making it an important target for drug discovery and development. Its unique structure and reactivity also make it valuable for the synthesis of other organic compounds, and it is often used as a precursor in the preparation of more complex molecules. Overall, 5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester is a versatile chemical with potential applications in both the pharmaceutical and chemical industries.

InChI:InChI=1/C6H4BrNO4S/c1-12-6(9)4-2-3(8(10)11)5(7)13-4/h2H,1H3

Upstream product

• 7311-63-9 5-bromothiophene-2-carboxylic acid 
• 62224-19-5 5-bromo-2-thiophenecarboxylic acid methyl ester 

Downstream Products

• 89499-35-4 4-Amino-5-bromo-thiophene-2-carboxylic acid; hydrobromide 
• 395664-69-4 5-(4-dodecyloxy-phenyl)-4-fluoro-thiophene-2-carboxylic acid methyl ester 
• 395664-59-2 methyl 5-bromo-4-fluorothiophene-2-carboxylate 
• 32431-75-7 methyl 4-fluorothiophene-2-carboxylate 
• 78399-05-0 5-anilino-4-nitro-thiophene-2-carboxylic acid methyl ester 
• 542-11-0 aniline hydrobromide 
• 159334-03-9 methyl 4-nitro-5-phenoxythiophene-2-carboxylate 
• 78399-18-5 5-(4-Methoxycarbonyl-phenylamino)-4-nitro-thiophene-2-carboxylic acid methyl ester 
• 78399-11-8 5-(3-Chloro-phenylamino)-4-nitro-thiophene-2-carboxylic acid methyl ester 
• 78398-92-2 5-(4-Methoxy-phenylamino)-4-nitro-thiophene-2-carboxylic acid methyl ester 
• 78398-98-8 4-Nitro-5-p-tolylamino-thiophene-2-carboxylic acid methyl ester 
• 89283-24-9 5-bromo-4-nitro-thiophene-2-carboxylic acid 

Relevant articles and documents

Thiophene compounds and applications of thiophene compounds serving as USP7 inhibitors and antitumor drugs

The invention discloses compounds shown in the formula I or nitrogen oxides, pharmaceutically acceptable salt or solvate of the compounds, a preparation method of the compounds, and applications of the compounds in pharmacy, and particularly provides the applications of the compounds serving as USP7 inhibitors and antitumor drugs. Pharmacodynamic experiment results show that the compounds in the formula I have inhibition effects on a USP7 enzyme and also have proliferation inhibition effects on human colon cancer cells HCT-116. Therefore, the compounds can be used for preparing the drugs for preventing or treating diseases related to tumors. The formula I is shown in the description.