38239-32-6 Usage
Uses
Used in Pharmaceutical Research:
5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester is utilized as a key intermediate in the synthesis of pharmaceutical compounds due to its unique structure and reactivity. It is particularly recognized for its antimicrobial and anticancer properties, which make it an important target for drug discovery and development.
Used in Organic Synthesis:
In the field of organic synthesis, 5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester serves as a versatile precursor for the preparation of more complex organic molecules. Its ability to participate in various chemical reactions contributes to the creation of a wide range of compounds, enhancing its utility in chemical research and development.
Used in Chemical Industry:
5-Bromo-4-nitrothiophene-2-carboxylic acid methyl ester is also applied within the chemical industry for its potential in creating new materials and compounds. Its diverse applications in this sector highlight its importance in advancing chemical processes and product development.
Check Digit Verification of cas no
The CAS Registry Mumber 38239-32-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,2,3 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 38239-32:
(7*3)+(6*8)+(5*2)+(4*3)+(3*9)+(2*3)+(1*2)=126
126 % 10 = 6
So 38239-32-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H4BrNO4S/c1-12-6(9)4-2-3(8(10)11)5(7)13-4/h2H,1H3
38239-32-6Relevant academic research and scientific papers
Thiophene compounds and applications of thiophene compounds serving as USP7 inhibitors and antitumor drugs
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Paragraph 0047; 0049; 0050, (2019/01/16)
The invention discloses compounds shown in the formula I or nitrogen oxides, pharmaceutically acceptable salt or solvate of the compounds, a preparation method of the compounds, and applications of the compounds in pharmacy, and particularly provides the applications of the compounds serving as USP7 inhibitors and antitumor drugs. Pharmacodynamic experiment results show that the compounds in the formula I have inhibition effects on a USP7 enzyme and also have proliferation inhibition effects on human colon cancer cells HCT-116. Therefore, the compounds can be used for preparing the drugs for preventing or treating diseases related to tumors. The formula I is shown in the description.
Ring fluorinated thiophenes: Applications to liquid crystal synthesis
Kiryanov, Andre A.,Seed, Alexander J.,Sampson, Paul
, p. 8797 - 8800 (2007/10/03)
Ring fluorinated thiophenes were synthesized via a Balz-Schiemann fluorination approach and were successfully employed in the synthesis of liquid crystals using regioselective electrophilic bromination and regioselective Suzuki coupling chemistry.