853-83-8Relevant articles and documents
Utilization of transition metal fluoride-based solid support catalysts for the synthesis of sulfonamides: Carbonic anhydrase inhibitory activity and: In silico study
Al-Rashida, Mariya,Ali, Deedar,Amjad, Sayyeda Tayyeba,Hameed, Abdul,Iftikhar, Shafia,Iqbal, Jamshed,Naseer, Muhammad Moazzam,Shafique, Zainab,Shah, Muhammad Raza,Sindhu, Tayyaba Allamgir
, p. 3165 - 3179 (2022/02/05)
The applications of solid support catalysts in catalyzing organic reactions are well-evident. In the present study, we explored a transition metal fluoride (FeF3) adsorbed on molecular sieves (4 ?) as a solid support catalyst for the preparation of sulfon
Pd(II)/(S)-t-BuPyOx-catalyzed asymmetric addition of arylboronic acids to N-sulfonyl-arylaldimines
Song, Kaixuan,Wen, Min,Shen, Kai,Fan, Chaogang,Yang, Zhenyu,Lin, Shaohui,Pan, Qinmin
supporting information, (2021/05/26)
The asymmetric version of Pd(II)/bipyridine-catalyzed nucleophilic addition of arylboronic acids to N-sulfonyl arylaldimines was developed, and excellent asymmetric induction was achieved by the use of chiral pyridinooxazoline ligand (S)-t-BuPyOx. Moistur
Site-Selective Electrochemical Benzylic C?H Amination
Hou, Zhong-Wei,Liu, Ding-Jin,Xiong, Peng,Lai, Xiao-Li,Song, Jinshuai,Xu, Hai-Chao
supporting information, p. 2943 - 2947 (2020/12/11)
C?H/N-H cross-coupling is an ideal strategy to synthesize various amines but remains challenging owing to the requirement for sacrificial chemical oxidants and the difficulty in controlling the regio- and chemo-selectivity. Herein we report a site-selective electrochemical amination reaction that can convert benzylic C?H bonds into C-N linkages via H2 evolution without need for external oxidants or metal catalysts. The synthetic strategy involves anodic cleavage of benzylic C?H to form a carbocation intermediate, which is then trapped with an amine nucleophile leading to C?N bond formation. Key to the success is to include HFIP as a co-solvent to modulate the oxidation potentials of the alkylbenzene substrate and the aminated product to avoid overoxidation of the latter.