38350-87-7

Usage

Chemical Properties

white micro-crystalline powder

InChI:InChI=1/C14H20O2/c1-2-3-4-5-6-7-12-8-10-13(11-9-12)14(15)16/h8-11H,2-7H2,1H3,(H,15,16)

Upstream product

• 79-37-8 oxalyl dichloride 
• 1078-71-3 heptylbenzene 
• 49763-67-9 4-heptylbenzaldehyde 
• 586-76-5 4-Bromobenzoic acid 
• 13125-66-1 n-heptylmagnesium bromide 
• 50606-96-7 4-heptylbenzoyl chloride 

Downstream Products

• 103177-40-8 8-(p-heptylbenzoyl)amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran 
• 103195-07-9 4-Heptyl-N-[3-(1H-tetrazol-5-yl)-2,3-dihydro-benzo[1,4]dioxin-5-yl]-benzamide 
• 50606-96-7 4-heptylbenzoyl chloride 
• 201600-36-4 1,2-Bis-(4-heptyl-phenyl)-ethane-1,2-dione 
• 331833-86-4 methyl 2-(4-heptylphenyl)-1-benzofuran-5-carboxylate 
• 881648-60-8 5-(4-benzyloxyphenyl)-2-[4-(4-heptylbenzoyl)-phenyl]-1,3,4-oxadiazole 
• 279675-92-2 2,5-bis[4-(4-heptylbenzoyl)-phenyl]-1,3,4-oxadiazole 
• 205862-09-5 3a,6a-Bis-(4-heptyl-phenyl)-tetrahydro-imidazo[4,5-d]imidazole-2,5-dione 
• 205862-12-0 C₅₂H₇₂N₆O₈ 

Relevant academic research and scientific papers

4-n-Heptylbenzoic Acid

Molecules of 4-n-heptylbenzoic acid, C14H20O2, occur as hydrogen-bonded dimers about crystallographic inversion centres.

Palladium catalyzed cross-coupling reaction of Grignard reagents with halobenzoic acids, halophenols and haloanilines

Convenient syntheses of substituted benzoic acids, phenols and anilines have been achieved by using palladium catalyzed cross-coupling reactions between Grignard reagents and aryl halides containing carboxy, hydroxy and amino groups without a protection-deprotection sequence.

Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia

α-Phosphonosulfonate compounds are provided which inhibit the enzyme squalene synthetase and thereby inhibit cholesterol biosynthesis. These compounds have the formula STR1 wherein R2 is OR5 or R5a ; R3 and R5 are independently H, alkyl, arylalkyl, aryl or cycloalkyl; R5a is H, alkyl, arylalkyl or aryl; R4 is H, alkyl, aryl, arylalkyl, or cycloalkyl;, Z is H, halogen, lower alkyl or lower alkenyl; and R1 is a lipophilic group which contains at least 7 carbons and is alkyl, alkenyl, alkynyl, mixed alkenyl-alkynyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, heteroaryl, heteroarylalkyl, cycloheteroalkyl, cycloheteroalkylalkyl; as further defined above; including pharmaceutically acceptable salts and or prodrug esters of the phosphonic (phosphinic) and/or sulfonic acids.

New potent antagonists of leukotrienes C4 and D4. 1. Synthesis and structure-activity relationships

(p-Amylcinnamoyl)anthranilic acid (3a) had moderate antagonist activities against LTD4-induced smooth muscle contraction on guinea pig ileum and LTC4-induced bronchoconstriction in anesthetized guinea pigs. Modifications were made in the hydrophobic part (cinnamoyl moiety) and the hydrophilic part (anthranilate moiety) of 3a. A series of 8-(benzoylamino)-2-tetrazol-5-yl-1,4-benzodioxans and 8-(benzoylamino)-2-tetrazol-5-yl-4-oxo-4H-1-benzopyrans were revealed to be potent antagonists of leukotrienes C4 and D4. Among both series, ONO-RS-347 (18k) and ONO-RS411 (19h) were the most potent and orally active antagonists, respectively. Structure-activity relationships are discussed.

Cyano-substituted biphenyl compounds and liquid crystalline dielectrics containing the same

Biphenyl derivatives of the formula: STR1 wherein X is --CO--O-- or --O--CO--, R1 and R4 are alkyl of 1 to 10 carbon atoms, and one of R2 and R3 is CN and the other is H, are useful for lowering the dielectric anisotropy of liquid crystalline dielectrics.