38428-05-6

Upstream product

• 64-17-5 ethanol 
• 65164-84-3 O,O-diphenyl {[(benzyloxy)carbonyl]amino}(phenyl)methylphosphonate 
• 621-84-1 O-benzyl carbamate 
• 100-52-7 benzaldehyde 
• 762-04-9 phosphonic acid diethyl ester 
• 100-51-6 benzyl alcohol 
• 38654-91-0 2-(diethoxyphosphino)-2-phenylacetic acid 
• 18108-22-0 1-amino-1-phenylmethylphosphonic acid 
• 501-53-1 benzyl chloroformate 
• 372199-85-4 [phenyl-(toluene-4-sulfonyl)-methyl]-carbamic acid benzyl ester 
• 13716-45-5 diethyl trimethylsilyl phosphite 
• 21646-99-1 diphosphorous acid tetraethyl ester 
• 169829-04-3 N,N'-benzylidenebis(benzyl carbamate) 
• 3266-66-8 acetyl diethyl phosphite 

Downstream Products

• 16814-08-7 diethyl 1-aminophenylmethylphosphonate 
• 38428-08-9 ethyl hydrogen α-(benzyloxycarbonylamino)benzylphosphonate 
• 53558-71-7 Diethyl-α-Aminobenzylphosphonato-hydrobromid 
• 146304-21-4 C₂₉H₃₈N₂O₈P₂ 
• 146304-11-2 [(2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-phenyl-methyl]-phosphonic acid diethyl ester 
• 146304-07-6 [(2-tert-Butoxycarbonylamino-acetylamino)-phenyl-methyl]-phosphonic acid diethyl ester 
• 38428-13-6 2-Benzyloxy-carbonylglycylamino-benzylphosphonsaeure-diaethylester 

Relevant academic research and scientific papers

Improved facile synthesis of α-amino phosphonates by the reaction of α-amido sulfones with dialkyl trimethyl silyl phosphites catalyzed by Fe(III) chloride

An improved efficient synthesis of α-amino phosphonates has been discovered by the reaction of N-benzyloxycarbonylamino sulfones with dialkyl trimethyl silyl phosphites in the presence of FeCl3as a catalyst. The products were formed in high yie

Acyloxy derivatives of trivalent phosphorus in amidoalkylation of hydrophosphoryl compounds

In order to model the previously suggested mechanism of the P-C bond formation via the Arbuzov reaction, we have studied the interaction of diethylacylphosphite (prepared beforehand as well as generated in situ from tetraethylpyrophosphite) with the in situ generated acyliminium cation. Various conditions of in situ generation of acylphosphite derivatives of P(III) from hydrophosphoryl compounds and acyliminium ions from N,N′- alkylidenebiscarbamates have been investigated: solvent nature, acid catalyst, and the reagents mixing order). The results obtained have confirmed the suggested mechanism of three-component reaction of amidoalkylation of hydrophosphoryl compounds with the formation of P-C bond via the Arbuzov reaction of in situ formed intermediates.

The synthesis of N-(β-triphenylgermanyl)-propionyl-α-amino-benzylphosphonates

A series of N-(β-triphenylgermanyl)propionyl-α-amino-benzylphosphonates was synthesized by reaction of β-triphenylgermanyl propionic acid with α-aminophosphonates under very mild conditions. The structures of products were determined by 1H NMR,

STUDIES ON ORGANOPHOSPHORUS COMPOUNDS. 65, A FACILE SYNTHETIC ROUTE TO PHOSPHONOPEPTIDES

A direct procedure for the preparation of phosphonopeptides, containing either a N- or C-terminal phosphonic acid residue, is described.This method is based on a three component condensation reaction leading to diethyl 1-(N-carbobenzyloxyamino)-alkylphosp