38453-73-5

Upstream product

• 67-56-1 methanol 
• 92428-42-7 (E)-4'-chlorostilbene-1-carboxylic acid 
• 1073-67-2 4-vinylbenzyl chloride 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 38453-65-5 3-(4-chlorobenzyl)isobenzofuran-1(3H)-one 
• 27326-43-8 2-vinylbenzoic acid 
• 637-87-6 1-Chloro-4-iodobenzene 

Downstream Products

• 92428-42-7 (E)-4'-chlorostilbene-1-carboxylic acid 
• 23909-29-7 2-(4-chlorophenyl)-1H-indene 
• 108683-66-5 C₁₅H₁₂Cl₂ 
• 38453-78-0 4'-Chlor-2-hydroxymethyl-trans-stilben 

Relevant academic research and scientific papers

Asymmetric protonation of ketone enolates using chiral β- hydroxyethers: Acidity-tuned enantioselectivity

New chiral hydroxyethers 1a-f were prepared for asymmetric protonation of achiral enolates prepared from prochiral ketones. The enantioselectivity of protonation was highly dependent upon the acidity of the chiral alcohols, the highest enantioselectivity

Copper-Catalyzed Enantioselective Hydroalkoxylation of Alkenols for the Synthesis of Cyclic Ethers

The copper-catalyzed enantioselective intramolecular hydroalkoxylation of unactivated alkenes for the synthesis of tetrahydrofurans, phthalans, isochromans, and morpholines from 4- and 5-alkenols is reported. The substrate scope is complementary to existing enantioselective alkene hydroalkoxylations and is broad with respect to substrate backbone and alkene substitution. The asymmetric induction and isotopic labeling studies support a polar/radical mechanism involving enantioselective oxycupration followed by C-[Cu] homolysis and hydrogen atom transfer. Synthesis of the antifungal insecticide furametpyr was accomplished.

An Easy-to-Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization

Flow electrochemistry is an efficient methodology to generate radical intermediates. An electrochemical flow microreactor has been designed and manufactured to improve the efficiency of electrochemical flow reactions. With this device only little or no supporting electrolytes are needed, making processes less costly and enabling easier purification. This is demonstrated by the facile synthesis of amidyl radicals used in intramolecular hydroaminations to produce isoindolinones. The combination with inline mass spectrometry facilitates a much easier combination of chemical steps in a single flow process.

Selenium-mediated synthesis of biaryls through rearrangement

"Chemical Equation Presented" A new cyclization of β-keto ester substituted stilbene derivatives using selenium electrophiles in the presence of Lewis acids is described. Substituted naphthols are obtained through cyclization and subsequent 1,2-rearrangement of aryl groups under very mild reaction conditions.