38574-09-3Relevant articles and documents
Synthesis of Functionalized Aliphatic Acid Esters via the Generation of Alkyl Radicals from Silylperoxyacetals
Matsumoto, Akira,Shiozaki, Yoko,Sakurai, Shunya,Maruoka, Keiji
supporting information, p. 2431 - 2434 (2021/08/07)
We describe a catalytic method for the synthesis of a variety of functionalized aliphatic acid esters using silylperoxyacetals, which are versatile alkyl radical precursors with a terminal ester moiety. In the presence of an appropriate transition-metal catalyst, the in situ generation of alkyl radicals and the subsequent bond-forming process proceeds smoothly to afford synthetically valuable aliphatic acid derivatives. The present method can be applied to the efficient synthesis of a pharmaceutically important 1,1-diarylalkane motif. In addition, a novel strategy for the synthesis of structurally diverse hydroxy acid derivatives via a C?O bond formation process that utilizes TEMPO has been developed.
Iron(III) tosylate in the preparation of dimethyl and diethyl acetals from ketones and β-keto enol ethers from cyclic β-diketones
Mansilla, Horacio,Afonso, Maria M.
, p. 2607 - 2618 (2008/12/22)
An efficient method for conversion of ketones to their corresponding dimethyl and diethyl acetals and of cyclic β-diketones into β-keto enol ethers using Fe(OTs)3 as a catalyst is described. Copyright Taylor & Francis Group, LLC.
Simple method for the preparation of dimethyl acetals from ketones with montmorillonite K 10 and p-toluenesulfonic acid
Mansilla, Horacio,Regas, David
, p. 2195 - 2201 (2007/10/03)
A simple method for conversion of ketones to their corresponding dimethyl acetals using montmorillonite K 10 and p-toluenesulfonic acid as acidic cocatalysts under very mild reaction conditions is described. Copyright Taylor & Francis Group, LLC.