2-Methylcyclohexanone dimethyl acetal

Base Information

• Chemical Name: 2-Methylcyclohexanone dimethyl acetal
• CAS No.: 38574-09-3
• Molecular Formula: C9H18O2
• Molecular Weight: 158.241
• Mol file: 38574-09-3.mol

Synonyms:1,1-Dimethoxy-2-methyl-cyclohexan;2-Methylcyclohexanone dimethyl aetal;1,1-dimethoxy-2-methylcyclohexane;2-methylcyclohexanone dimethyl ketal;2-Methyl-cyclohexanon-dimethylacetal;2-Methyl-cyclohexanon-dimethylketal;

Chemical Property of 2-Methylcyclohexanone dimethyl acetal

Chemical Property:

• PSA: 18.46000
• LogP: 2.18560

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methylcyclohexanone dimethyl acetal

There total 5 articles about 2-Methylcyclohexanone dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 2-Methylcyclohexanone (583-60-8) → 1,1-dimethoxy-2-methylcyclohexane (38574-09-3)

Guidance literature:

With trimethyl orthoformate; at 80 ℃; for 8h; under 6000480 Torr;

DOI:10.1055/s-2005-872229

Reference yield: 76.0%

2-Methylcyclohexanone (583-60-8) + trimethyl orthoformate (149-73-5) → 1,1-dimethoxy-2-methylcyclohexane (38574-09-3)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; for 16h; Ambient temperature;

DOI:10.1021/ja00049a014

Reference yield:

methanol (67-56-1) + 2-methylmethoxybenzene (578-58-5) → 2-Methylcyclohexanol (583-59-5) + 1,1-dimethoxy-2-methylcyclohexane (38574-09-3) + cis-1-methoxy-2-methylcyclohexane (21547-36-4,32122-44-4,53273-15-7,109238-86-0) + methyl cyclohexane (82166-21-0)

Guidance literature:

With hydrogen; at 40 ℃; for 4h; under 11251.1 Torr; Inert atmosphere; Schlenk technique;

DOI:10.1039/c5cy00599j

upstream raw materials:

methanol

1-Methoxy-norcaran

2-Methylcyclohexanone

trimethyl orthoformate

Downstream raw materials:

(n-pr)3Si(Ome)

1-methoxy-2-methylcyclohexane

ethyl 4-<1-(hydroxyphenylmethyl)-2-methylcyclohexyl>-4-oxobutanoate

2-(1-Methoxy-2-methyl-cyclohexyl)-2-trimethylsilanyloxy-cyclobutanone