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Anthracene, 9-(4-fluorophenyl)-, also known as 9-(4-fluorophenyl)anthracene, is an organic compound with the chemical formula C20H13F. It is a derivative of anthracene, a tricyclic aromatic hydrocarbon, with a fluorophenyl group attached at the 9th position. Anthracene, 9-(4-fluorophenyl)- is characterized by its white to off-white crystalline appearance and is soluble in organic solvents. It is primarily used in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds due to its unique chemical structure and properties. The presence of the fluorine atom in the molecule can significantly influence its reactivity, stability, and biological activity, making it a valuable intermediate in the development of new chemical entities.

386-22-1

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386-22-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 386-22-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 386-22:
(5*3)+(4*8)+(3*6)+(2*2)+(1*2)=71
71 % 10 = 1
So 386-22-1 is a valid CAS Registry Number.

386-22-1Downstream Products

386-22-1Relevant academic research and scientific papers

When Anthracene and Quinone Avoid Cycloaddition: Acid-Catalyzed Redox Neutral Functionalization of Anthracene to Aryl Ethers

Ding, Nan,Ding, Nan,Ding, Nan,Li, Zhi

supporting information, p. 4276 - 4282 (2020/06/04)

Benzoquinone and 9-phenylanthracene barely undergo anticipated cycloaddition under acid catalysis. Instead, 9-anthracenyl aryl ethers are obtained as unexpected products. Mechanistic studies indicate that the reaction likely undergoes an ionic mechanism between protonated anthracene species and nucleophilic oxygen of 1,4-benzoquinone or 1,4-hydroquinone. A variety of 9-anthracenyl aryl ethers are constructed with this method. Produced anthracenyl aryl ethers are potential scaffolds for new fluorescent molecules.

Chromium- and Cobalt-Catalyzed, Regiocontrolled Hydrogenation of Polycyclic Aromatic Hydrocarbons: A Combined Experimental and Theoretical Study

Han, Bo,Ma, Pengchen,Cong, Xuefeng,Chen, Hui,Zeng, Xiaoming

supporting information, p. 9018 - 9026 (2019/06/13)

Polycyclic aromatic hydrocarbons are difficult substrates for hydrogenation because of the thermodynamic stability caused by aromaticity. We report here the first chromium- and cobalt-catalyzed, regiocontrolled hydrogenation of polycyclic aromatic hydrocarbons at ambient temperature. These reactions were promoted by low-cost chromium or cobalt salts combined with diimino/carbene ligand and methylmagnesium bromide and are characterized by high regioselectivity and expanded substrate scope that includes tetracene, tetraphene, pentacene, and perylene, which have rarely been reduced. The approach provides a cost-effective catalytic protocol for hydrogenation, is scalable, and can be utilized in the synthesis of tetrabromo- and carboxyl-substituted motifs through functionalization of the hydrogenation product. The systematic theoretical mechanistic modelings suggest that low-valent Cr and Co monohydride species, most likely from zerovalent transition metals, are capable of mediating these hydrogenations of fused PAHs.

Suzuki-Miyaura cross-coupling of bulky anthracenyl carboxylates by using pincer nickel N-heterocyclic carbene complexes: An efficient protocol to access fluorescent anthracene derivatives

Xu, Mizhi,Li, Xingbao,Sun, Zheming,Tu, Tao

supporting information, p. 11539 - 11541 (2013/12/04)

A series of fluorescent (hetero)-aryl substituted anthracene derivatives were readily accessible from the corresponding bulky anthracen-9-yl carboxylates via Suzuki-Miyaura cross-coupling reactions by using pincer nickel N-heterocyclic carbene complex 1 even at the catalyst loading as low as 0.1 mol% in the presence of catalytic amounts of PCy3.

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