386-72-1

Basic information

• Product Name: 2-NITRO-3-(TRIFLUOROMETHYL)PHENOL
• Synonyms: 2-NITRO-3-(TRIFLUOROMETHYL)PHENOL;alpha,alpha,alpha-trifluoro-2-nitro-m-cresol;2-Nitro-3-(trifluoromethyl)phenol, 2-Hydroxy-6-(trifluoromethyl)nitrobenzene;3-Hydroxy-2-nitrobenzotrifluoride
• CAS NO: 386-72-1
• Molecular Formula: C₇H₄F₃NO₃
• Molecular Weight: 207.11
• Mol File: 386-72-1.mol

Chemical Properties

• Boiling Point: 236.4±40.0 °C(Predicted)
• Appearance: /
• Density: 1.554±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 5.66±0.10(Predicted)
• CAS DataBase Reference: 2-NITRO-3-(TRIFLUOROMETHYL)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NITRO-3-(TRIFLUOROMETHYL)PHENOL(386-72-1)
• EPA Substance Registry System: 2-NITRO-3-(TRIFLUOROMETHYL)PHENOL(386-72-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 386-72-1(Hazardous Substances Data)

Usage

Uses

Used in Fungicidal Applications:
2-Nitro-3-(trifluoromethyl)phenol is used as a fungicide for controlling fungal growth in various settings. Its chemical structure allows it to inhibit essential fungal processes, providing protection against a range of fungal pathogens.
Used in Pharmaceutical Industry:
2-Nitro-3-(trifluoromethyl)phenol is used as an intermediate in the synthesis of aniline derivatives, such as 2-Amino-3-trifluoromethylphenol (A630795). These aniline derivatives have potential applications in the development of new pharmaceuticals, including those with antibacterial, antifungal, and antiviral properties.
Used in Chemical Synthesis:
In the chemical industry, 2-Nitro-3-(trifluoromethyl)phenol serves as a key intermediate for the production of various specialty chemicals, including dyes, pigments, and polymers. Its unique functional groups make it a valuable building block for creating complex molecular structures with specific properties and applications.

Upstream product

• 98-17-9 3-Trifluoromethylphenol 
• 384-22-5 2-nitrobenzotrifluoride 
• 386-71-0 2-nitro-3-(trifluoromethyl)aniline 

Downstream Products

• 106877-48-9 2-amino-3-(trifluoromethyl)phenol 
• 914635-64-6 2-bromo-1-methoxy-3-(trifluoromethyl)benzene 
• 609850-67-1 C₂₃H₂₂F₇NO₂ 

Relevant articles and documents

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Hydroxylation of Nitroarenes with Alkyl Hydroperoxide Anions via Vicarious Nucleophilic Substitution of Hydrogen

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